Bergau Leonard, Bengel Philipp, Sciacca Vanessa, Fink Thomas, Sohns Christian, Sommer Philipp
Clinic for Electrophysiology, Herz- und Diabeteszentrum Nordrhein-Westfalen, Ruhr Universität Bochum, 32545 Bad Oeynhausen, Germany.
Department of Cardiology and Pneumology, Heart Center, University Medical Center, 37075 Goettingen, Germany.
J Clin Med. 2022 Apr 29;11(9):2510. doi: 10.3390/jcm11092510.
Atrial fibrillation (AF) is the most common sustained arrhythmia worldwide and has a strong association with heart failure (HF). It often remains unclear if HF is the cause or consequence of AF due to the complexity of the processes that are involved in both the perpetuation of AF and the development of HF. To date, two therapeutic strategies are accepted as the standard of care in AF patients with heart failure. Rhythm control aims to permanently restore sinus rhythm, whereas a rate-control strategy aims to slow ventricular rate without the termination of AF. In the last 5 years a tremendous number of important studies have been published investigating the optimal therapeutic strategy in HF patients. This review highlights the important studies with respect to the involvement of AF in promoting left-ventricular dysfunction and discusses the optimal strategy in HF patients suffering from AF.
心房颤动（AF）是全球最常见的持续性心律失常，与心力衰竭（HF）密切相关。由于房颤持续存在和心力衰竭发展过程的复杂性，HF究竟是AF的原因还是结果往往并不明确。迄今为止，两种治疗策略被公认为是心力衰竭合并房颤患者的标准治疗方法。节律控制旨在永久恢复窦性心律，而心率控制策略旨在减慢心室率而不终止房颤。在过去5年中，发表了大量重要研究，探讨心力衰竭患者的最佳治疗策略。本综述重点介绍了关于房颤在促进左心室功能障碍方面作用的重要研究，并讨论了心力衰竭合并房颤患者的最佳治疗策略。
