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单纯黏膜固定术与痔动脉结扎术(有无多普勒引导):一项关于短期疗效的随机临床试验

Simple mucopexy and hemorrhoidal arterial ligation with and without Doppler guide: a randomized clinical trial for short-term outcome.

作者信息

Alemrajabi Mahdi, Akbari Abolfazl, Sohrabi Sara, Rezazadehkermani Mohammad, Moradi Mohammad, Agah Shahram, Masoodi Mohsen

机构信息

Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.

Colorectal Research Center, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Ann Coloproctol. 2023 Aug;39(4):351-356. doi: 10.3393/ac.2022.00017.0002. Epub 2022 May 16.

Abstract

PURPOSE

Hemorrhoids are the most common benign anorectal diseases. Mucopexy strengthens the anal canal mucosa, which can be performed alone or in combination with Doppler-guided hemorrhoidal artery ligation (DG-HAL). In this study, we compared the postoperative complications between simple mucopexy plus HAL with and without a Doppler guide.

METHODS

This study was performed as a single-blinded randomized clinical trial. Patients referred to a tertiary colorectal referral clinic with grades 3 and 4 hemorrhoids who were candidates for surgical intervention entered the study. Thirty-six patients were randomly divided into 2 groups. Group A including 18 patients underwent mucopexy and DG-HAL and the other 18 patients (group B) underwent standard mucopexy and HAL without a Doppler guide. Postoperative pain score and the duration of oral analgesic consumption were recorded. Additionally, postoperative symptoms and complications were recorded and compared between the 2 methods.

RESULTS

There was no significant difference between the 2 groups in terms of pain score and the duration of postoperative analgesic consumption as well as the incidence of postoperative complications. Besides, the primary grade of hemorrhoids was not significantly associated with recurrence, but there was a significant association between body mass index and Wexner score (WS) with recurrence. The mean WS of patients showed a significant decrease in both groups postoperatively. However, the rate of WS reduction was not remarkably different between the 2 groups.

CONCLUSION

Simple mucopexy with blind HAL (without Doppler guide) might be considered for the treatment of grades 3 and 4 hemorrhoids effectively.

摘要

目的

痔疮是最常见的良性肛肠疾病。黏膜固定术可加强肛管黏膜,该手术可单独进行,也可与多普勒引导下痔动脉结扎术(DG-HAL)联合进行。在本研究中,我们比较了单纯黏膜固定术加HAL在有或没有多普勒引导情况下的术后并发症。

方法

本研究为单盲随机临床试验。被转诊至三级结直肠转诊诊所、患有3级和4级痔疮且适合手术干预的患者纳入研究。36例患者随机分为2组。A组18例患者接受黏膜固定术和DG-HAL,另外18例患者(B组)接受标准黏膜固定术和无多普勒引导的HAL。记录术后疼痛评分和口服镇痛药使用时间。此外,记录并比较两种方法的术后症状和并发症。

结果

两组在疼痛评分、术后镇痛药物使用时间以及术后并发症发生率方面均无显著差异。此外,痔疮的初始分级与复发无显著相关性,但体重指数和韦克斯纳评分(WS)与复发有显著相关性。两组患者术后的平均WS均显著降低。然而,两组之间WS降低率没有显著差异。

结论

单纯黏膜固定术联合盲目HAL(无多普勒引导)可能是治疗3级和4级痔疮的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2430/10475797/ae89aad75e89/ac-2022-00017-0002f1.jpg

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