Link Rafaela A, Link Carlos A, Benin Lima Matheus H, Pasetti Bruna W, Savaris Ricardo F
Obstetrics and Gynecology Department, Universidade de Passo Fundo, Faculdade de Medicina, Passo Fundo, BRA.
Surgical Sciences, Universidade Federal do Rio Grande do Sul, Postgraduate Program in Medicine, Porto Alegre, BRA.
Cureus. 2022 Apr 13;14(4):e24109. doi: 10.7759/cureus.24109. eCollection 2022 Apr.
Introduction (CT) has been related to fallopian tube damage and infertility. Its prevalence in the population that attend public services is known; however, there is scant data on this factor in private infertility clinics. The objective of this study is to verify the prevalence of CT among women attending a private in vitro fertilization (IVF) reference clinic in southern Brazil. Methods This is a cross-sectional study carried out between January 1, 2019, and August 30, 2021, at an IVF private clinic in southern Brazil. Infertile women between 18 and 50 years old, who provided a morning urinary sample for reverse transcription-polymerase chain reaction(RT-PCR) test for CT analysis, were included in the study. The variables studied included the patient's age, body mass index (BMI), duration of infertility, type of infertility, indication for IVF, and detection or not of CT in the urine. Results The prevalence of CT was 10.84% (22 out of 203; 95% CI: 7.27-15.87). Patients with secondary infertility were older and had more ovarian and tubal factors compared to cases of primary infertility. The tubal factor was the most prevalent (27.3% in women with primary infertility and 35.8% in those with secondary). Time of infertility and BMI were similar between groups. Our results are derived from a single private IVF clinic which reduces the external validity. Conclusion The prevalence of 10.84% of CT in this population raises the importance of screening for sexually transmitted infections for proper treatment and to achieve better IVF outcomes.
引言 沙眼衣原体（CT）与输卵管损伤和不孕症有关。其在就诊于公共服务机构人群中的患病率是已知的；然而，关于私立不孕不育诊所中这一因素的数据却很少。本研究的目的是核实巴西南部一家私立体外受精（IVF）参考诊所就诊女性中CT的患病率。方法 这是一项横断面研究，于2019年1月1日至2021年8月30日在巴西南部一家私立IVF诊所开展。纳入年龄在18至50岁之间、提供晨尿样本用于CT分析的逆转录-聚合酶链反应（RT-PCR）检测的不孕女性。研究的变量包括患者年龄、体重指数（BMI）、不孕持续时间、不孕类型、IVF指征以及尿液中CT的检测情况。结果 CT的患病率为10.84%（203例中有22例；95%置信区间：7.27 - 15.87）。与原发性不孕病例相比，继发性不孕患者年龄更大，卵巢和输卵管因素更多。输卵管因素最为常见（原发性不孕女性中占27.3%，继发性不孕女性中占35.8%）。两组之间不孕时间和BMI相似。我们的结果来自单一的私立IVF诊所，这降低了外部有效性。结论 该人群中CT患病率为10.84%，这凸显了筛查性传播感染以进行恰当治疗并实现更好IVF结果的重要性。
