Turmel Jean-Marie, Olive Claude, Bigeard Bastien, Abel Sylvie, Banydeen Rishika, Daoud Laura, Fayolle Pierre-Marie, Cabié André
Am J Trop Med Hyg. 2022 May 16;107(1):97-9. doi: 10.4269/ajtmh.21-1102.
We report the case of an 83-year-old woman with acute, febrile respiratory failure resulting from interstitial pneumonia that required high-flow oxygen therapy. This clinical picture, associated with the ongoing epidemiological situation, initially guided us toward a diagnosis of COVID-19. Based on SARS-CoV-2 reverse transcription-polymerase chain reaction negativity and the absence of anti-SARS-CoV-2 antibodies, a search for a differential diagnosis was conducted that led us to conclude a diagnosis of severe pulmonary leptospirosis This case highlights the need to engage in early discussions about differential diagnoses, including neglected tropical and subtropical diseases, during the COVID-19 era.
我们报告了一例83岁女性患者，因间质性肺炎导致急性发热性呼吸衰竭，需要高流量氧疗。结合当前的流行病学情况，这种临床表现最初使我们倾向于诊断为COVID-19。基于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）逆转录聚合酶链反应阴性以及抗SARS-CoV-2抗体阴性，我们进行了鉴别诊断，最终确诊为严重肺型钩端螺旋体病。该病例强调了在COVID-19疫情期间，需要尽早开展关于鉴别诊断的讨论，包括被忽视的热带和亚热带疾病。
