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孟加拉国的钩端螺旋体病与新冠病毒共同感染病例。

Leptospirosis and COVID-19 co-infection case in Bangladesh.

作者信息

Amin Mohammad Ashraful, Nahin Sabrina, Bonna Atia Sharmin, Kabir Rozars Md Faisal, Hossain Hawlader Mohammad Delwer

机构信息

Department of Public Health, North South University, Dhaka, 1229, Bangladesh.

Public Health Professional Development Society (PPDS), Dhaka, 1215, Bangladesh.

出版信息

Heliyon. 2022 Nov 24;8(11):e11828. doi: 10.1016/j.heliyon.2022.e11828. eCollection 2022 Nov.

Abstract

INTRODUCTION

Leptospirosis, a zoonotic illness, is comparable to COVID-19 in that the majority of infections are mild or asymptomatic, and only a tiny percentage of those infected experience multiple system affected. coinfection and the pathogenesis of SARS-CoV-2(Severe Acute Respiratory Syndrome Coronavirus 2) play a significant part in the emergence and progression of SARS-CoV-2 infection by enhancing the difficulty of identification, management, and outcome of COVID-19 well as worsening disease severity and death.

CASE REPORT

We presented a 47-year-old individual with diagnosed with SARS-CoV-2. A rapid test for IgM antibodies was used to confirm . Reverse-transcription Polymerase Chain Reaction was used to establish COVID-19 (RTPCR). During the COVID-19 emergent crisis in Chattogram, Bangladesh, the person was diagnosed and treated with functional, supportive care for COVID-19 and antibiotic therapy for leptospirosis. The patient was given medication and guidance before being discharged from the hospital.To highlight the importance of microbial coinfection in COVID-19, we outline the coinfection of bacteria with SARS-CoV-2, their effects on COVID-19, the grounds for coinfection, and their identification.

摘要

引言

钩端螺旋体病是一种人畜共患病,与新冠肺炎类似,大多数感染为轻症或无症状,只有极少数感染者会出现多系统受累。新冠病毒(严重急性呼吸综合征冠状病毒2)的合并感染及其发病机制在新冠病毒感染的发生和发展中起着重要作用,它增加了新冠肺炎的识别、管理难度以及影响其预后,同时还会加重疾病严重程度和导致死亡。

病例报告

我们报告了一名47岁确诊感染新冠病毒的患者。通过快速检测IgM抗体进行确诊。采用逆转录聚合酶链反应(RTPCR)来确诊新冠肺炎。在孟加拉国吉大港的新冠肺炎紧急危机期间,该患者被诊断出感染新冠病毒,并接受了针对新冠肺炎的功能支持性治疗以及针对钩端螺旋体病的抗生素治疗。患者在出院前接受了药物治疗和指导。为强调微生物合并感染在新冠肺炎中的重要性,我们概述了细菌与新冠病毒的合并感染情况、它们对新冠肺炎的影响、合并感染的原因以及它们的识别方法。

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