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体外受精与人类精子密度和活力之间的相关性。

Correlation between in vitro fertilization and human sperm density and motility.

作者信息

Gerris J, Khan I

出版信息

J Androl. 1987 Jan-Feb;8(1):48-54. doi: 10.1002/j.1939-4640.1987.tb02419.x.

DOI:10.1002/j.1939-4640.1987.tb02419.x
PMID:3558110
Abstract

The conventional sperm characteristics of density (millions per milliliter) and motility, scored in a semi-subjective way, were correlated with results of an on-going in vitro fertilization and embryo transfer program. No male infertility patients were included in this study. Individual characteristics of the "successful" ejaculates are described. Sperm densities in the original ejaculate of more than 10 X 10(6) spermatozoa/ml did not significantly improve outcome (P less than 0.01). In contrast, sperm motility seemed to play the most important role, since most pregnancies (12/14) occurred using sperm samples with greater than or equal to 60% total motility (P less than 0.001). The incidence of multipronuclear fertilization is also described and discussed. These data, which were collected during 1984 in the in vitro fertilization unit of Professor R. Schoysman and coworkers (Vilvoorde, Brussels), may help to make fertilization in vitro and embryo transfer a viable method in cases of mild male subfertility, and to provide guidance in preparing some couples for the combined use of husband and donor semen if a sufficient number of oocytes are obtained.

摘要

以半主观方式评分的传统精子密度(每毫升百万个)和活力特征,与正在进行的体外受精和胚胎移植项目的结果相关。本研究未纳入男性不育患者。描述了“成功”射精的个体特征。原始射精中精子密度超过10×10⁶个精子/毫升并不能显著改善结果(P<0.01)。相比之下,精子活力似乎起着最重要的作用,因为大多数妊娠(12/14)发生在总活力大于或等于60%的精子样本中(P<0.001)。还描述并讨论了多原核受精的发生率。这些数据于1984年在R. Schoysman教授及其同事(布鲁塞尔维尔沃德)的体外受精单元收集,可能有助于使体外受精和胚胎移植成为轻度男性生育力低下病例的可行方法,并在获得足够数量卵母细胞时,为一些夫妇联合使用丈夫和供体精液提供指导。

相似文献

1
Correlation between in vitro fertilization and human sperm density and motility.体外受精与人类精子密度和活力之间的相关性。
J Androl. 1987 Jan-Feb;8(1):48-54. doi: 10.1002/j.1939-4640.1987.tb02419.x.
2
Minimal requirements for ejaculates used for in vitro fertilization.用于体外受精的精液的最低要求。
Arch Androl. 1984;12(1):69-77. doi: 10.3109/01485018409161152.
3
Outcome of donor versus husband insemination in couples with unexplained infertility treated by in vitro fertilization and embryo transfer.体外受精与胚胎移植治疗的不明原因不孕夫妇中供体授精与丈夫授精的结局
Fertil Steril. 1994 Jun;61(6):1088-91. doi: 10.1016/s0015-0282(16)56761-2.
4
Comparison of sperm parameters, in vitro fertilization results, and subsequent pregnancy rates using sequential ejaculates, collected two hours apart, from oligoasthenozoospermic men.对少弱精子症男性每隔两小时采集的连续射精样本的精子参数、体外受精结果及后续妊娠率进行比较。
Fertil Steril. 1995 Nov;64(5):1008-11. doi: 10.1016/s0015-0282(16)57920-5.
5
Correlation of computerized semen analysis with successful fertilization of oocytes in an in vitro fertilization program.计算机辅助精液分析与体外受精程序中卵母细胞成功受精的相关性。
Arch Androl. 1990;24(3):229-34. doi: 10.3109/01485019008987579.
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[Measurement of sperm motility by Laser-Doppler-spectroscopy in routine andrology lab tests].[在常规男科学实验室检测中通过激光多普勒光谱法测量精子活力]
Andrologia. 1985 May-Jun;17(3):217-23.
7
Relationship between human in-vitro fertilization and intracytoplasmic sperm injection and the zona-free hamster egg penetration test.人类体外受精和卵胞浆内单精子注射与无透明带仓鼠卵穿透试验之间的关系。
Hum Reprod. 1998 Jul;13(7):1928-32. doi: 10.1093/humrep/13.7.1928.
8
Is spermatozoan acrosin a predictor of fertilization and embryo quality in the human?人类精子顶体蛋白酶是受精和胚胎质量的预测指标吗?
Fertil Steril. 1993 Nov;60(5):881-7. doi: 10.1016/s0015-0282(16)56291-8.
9
Morphology of seminal and swim-up spermatozoa and the outcome of in vitro fertilization and embryo transfer.精液及上游法处理后精子的形态与体外受精和胚胎移植的结局
Andrologia. 1990 Jul-Aug;22(4):369-75. doi: 10.1111/j.1439-0272.1990.tb02008.x.
10
Evaluation of a cut-off value for sperm motility after different hours of incubation to select the suitable reproductive technology (IVF or ICSI).评估不同孵育时间后的精子活力临界值,以选择合适的生殖技术(体外受精或卵胞浆内单精子注射)。
Acta Obstet Gynecol Scand. 1999 Apr;78(4):326-31.

引用本文的文献

1
Group-training of rams at puberty for artificial vagina-mediated semen collection and its influence on semen quality and sexual behavior.青春期公羊人工阴道采精的群体训练及其对精液质量和性行为的影响。
Anim Reprod. 2023 Apr 21;20(1):e20220051. doi: 10.1590/1984-3143-AR2022-0051. eCollection 2023.
2
Male infertility: evaluation of human sperm function and its clinical application.男性不育症:人类精子功能评估及其临床应用
J Endocrinol Invest. 1995 Jun;18(6):468-83. doi: 10.1007/BF03349748.
3
Accuracy of sperm characteristics in predicting the in vitro fertilizing capacity of semen.
精子特征对精液体外受精能力预测的准确性。
J In Vitro Fert Embryo Transf. 1988 Dec;5(6):326-31. doi: 10.1007/BF01129567.
4
Predictive value of sperm morphology and movement characteristics in the outcome of in vitro fertilization of human oocytes.
J In Vitro Fert Embryo Transf. 1989 Jun;6(3):142-8. doi: 10.1007/BF01130778.
5
The relationship between sperm parameters and fertilizing capacity in vitro: a predictive role for swim-up migration.精子参数与体外受精能力之间的关系:上游迁移的预测作用。
J In Vitro Fert Embryo Transf. 1990 Feb;7(1):38-44. doi: 10.1007/BF01133882.
6
Glass-bead column separation of motile and nonmotile human spermatozoa.玻璃珠柱法分离活动与不活动的人类精子。
J In Vitro Fert Embryo Transf. 1991 Apr;8(2):96-100. doi: 10.1007/BF01138662.