XX, Indian Council of Medical Research, V. Ramalingaswami Bhawan, Ansari Nagar, New Delhi-110029.
XX, Head Start Educational Academy, Sy. 98/1, Kommasandra, Dommasandra Post, Via Sarjapura, Bangalore-562125.
Int J Infect Dis. 2022 Aug;121:184-189. doi: 10.1016/j.ijid.2022.05.032. Epub 2022 May 15.
The global influenza surveillance and response system (GISRS), coordinated by the World Health Organization (WHO), is a global framework for surveillance of influenza and other respiratory viruses, data collection, laboratory capacity building, genomic data submission and archival, standardization, and calibration of reagents and vaccine strains, production of seasonal influenza vaccines and creating a facilitatory regulatory environment for the same. GAPS: WHO-designated national influenza centers (NICs) are entrusted with establishing surveillance in their respective countries. National and subnational surveillance remains weak in most parts of the world because of varying capacities of the NICs, lack of funds, poor human and veterinary surveillance mechanisms, lack of intersectoral coordination, and varying commitments of the local government.
As influenza viruses have a wide variety of nonhuman hosts, it is critical to strengthen surveillance at local levels for timely detection of untypable or novel strains with potential to cause epidemics or pandemics. In this article, we have proposed possible strategies to strengthen and expand local capacities for respiratory virus surveillance through the designated NICs of the WHO.
由世界卫生组织（WHO）协调的全球流感监测和应对系统（GISRS）是一个监测流感和其他呼吸道病毒、数据收集、实验室能力建设、基因组数据提交和存档、标准化和校准试剂和疫苗株、生产季节性流感疫苗以及为其创造有利监管环境的全球框架。
世界卫生组织指定的国家流感中心（NICs）负责在各自国家建立监测。由于 NICs 的能力不同、缺乏资金、人类和兽医监测机制不完善、部门间协调不力以及地方政府的承诺程度不同，世界上大多数地区的国家和次国家监测仍然薄弱。
由于流感病毒有多种非人类宿主，因此必须加强地方一级的监测，以便及时发现可能导致流行或大流行的无法定型或新型菌株。在本文中，我们提出了通过世界卫生组织指定的 NICs 加强和扩大呼吸病毒监测地方能力的可能策略。
