Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang Ming Chiao Tung University College of Medicine, Taipei, Taiwan; Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan.
J Formos Med Assoc. 2022 Nov;121(11):2324-2330. doi: 10.1016/j.jfma.2022.04.018. Epub 2022 May 16.
Generalized anxiety disorder (GAD) is the second most common psychiatric comorbidity of epilepsy. GAD has a negative impact on seizure control, and it is underrecognized. The Generalized Anxiety Disorder 7-item (GAD-7) questionnaire is useful for screening GAD in patients with epilepsy (PWE). This study aimed to validate the traditional Chinese version of the GAD-7 for Taiwanese patients by obtaining data on adult PWE from our hospital.
PWE were recruited from the Taipei Veterans General Hospital from April 2017 to January 2020. The mood disorder module of the Mini International Neuropsychiatric Interview (MINI) was used for the psychiatric assessment. The traditional Chinese version of the GAD-7 and the Beck Anxiety Inventory were included as self-rated psychiatric evaluation. To investigate the psychometric properties, internal consistency, external validation, and receiver operator characteristic (ROC) curve analysis were conducted to assess the utility of the Taiwanese version of the GAD-7.
We recruited 109 patients in the present study. Seventeen patients (15.9%) had GAD according to the MINI. The mean GAD-7 score was 10.28 ± 10.68. All the GAD-7 items were significantly and positively associated with the corrected overall GAD-7 score (Cronbach's alpha = 0.928, p < 0.0001). The cut-off point for the GAD-7 in ROC curve analysis was 7. The patients with GAD were more likely to be female and single.
The traditional Chinese version of the GAD-7 is a reliable and valid self-report questionnaire for detecting GAD in Taiwanese PWE.
广泛性焦虑障碍（GAD）是癫痫的第二大常见精神共病。GAD 会对癫痫患者的癫痫发作控制产生负面影响，但它未得到充分的认识。广泛性焦虑障碍 7 项量表（GAD-7）对于筛查癫痫患者中的 GAD 是有用的。本研究旨在通过从我们医院获取成年癫痫患者的数据，验证 GAD-7 的繁体中文版在台湾患者中的适用性。
从 2017 年 4 月至 2020 年 1 月，我们从台北荣民总医院招募了癫痫患者。使用迷你国际神经精神访谈（MINI）的心境障碍模块进行精神评估。繁体中文版 GAD-7 和贝克焦虑量表作为自评性精神评估。为了调查心理测量特性，进行了内部一致性、外部验证和受试者工作特征（ROC）曲线分析，以评估台湾版 GAD-7 的效用。
我们在本研究中招募了 109 名患者。根据 MINI，17 名患者（15.9%）患有 GAD。GAD-7 的平均得分为 10.28±10.68。所有 GAD-7 项目与校正后的总体 GAD-7 评分均呈显著正相关（克朗巴赫 α=0.928，p<0.0001）。ROC 曲线分析中 GAD-7 的截断点为 7。患有 GAD 的患者更可能为女性和单身。
繁体中文版 GAD-7 是一种可靠有效的自评问卷，可用于检测台湾癫痫患者的 GAD。
