MMWR Morb Mortal Wkly Rep. 2022 May 20;71(20):686-689. doi: 10.15585/mmwr.mm7120a3.
On June 16, 2021, rabies virus infection was confirmed in a dog included in a shipment of rescue animals imported into the United States from Azerbaijan. A multistate investigation was conducted to prevent secondary rabies cases, avoid reintroduction of a dog-maintained rabies virus variant (DMRVV), identify persons who might have been exposed and would be recommended to receive rabies postexposure prophylaxis, and investigate the cause of importation control failures. Results of a prospective serologic monitoring (PSM) protocol suggested that seven of 32 (22%) animals from the same shipment as the dog with confirmed rabies virus infection and who had available titer results after rabies vaccine booster had not been adequately vaccinated against rabies before importation. A requirement for rabies vaccination certificates alone will not adequately identify improper vaccination practices or fraudulent paperwork and are insufficient as a stand-alone rabies importation prevention measure. Serologic titers before importation would mitigate the risk for importing DMRVV.
2021 年 6 月 16 日,从阿塞拜疆进口到美国的一批救援动物中,一只狗被确诊感染了狂犬病病毒。为了防止继发狂犬病病例、避免再次引入犬源性狂犬病病毒变异株(DMRVV)、确定可能接触过病毒的人员并建议其接受狂犬病暴露后预防,以及调查进口控制失败的原因,开展了一项多州调查。一项前瞻性血清监测(PSM)方案的结果表明,在同批进口动物中,除了狂犬病病毒感染确诊的犬只之外,还有 32 只动物(22%)在接受狂犬病疫苗加强针后有可用的滴度结果,这些动物在进口前没有得到充分的狂犬病疫苗接种。仅依靠狂犬病疫苗接种证书不能充分识别出不适当的接种操作或伪造文件,而且作为单独的狂犬病进口预防措施是不够的。在进口前的血清学滴度可以降低引入 DMRVV 的风险。