Department of Physiology, College of Medicine, University of Sulaimani, Sulaimaniyah, Republic of Iraq.
Department of Medical Laboratory Sciences, Komar University of Science and Technology, Sulaimaniyah, Republic of Iraq.
Vet Med Sci. 2022 Jul;8(4):1769-1779. doi: 10.1002/vms3.814. Epub 2022 May 19.
Nanotechnology is a far-reaching technology with tremendous applications in various aspects, including general medicine, veterinary medicine, agriculture, aquaculture, and food production. Nanomaterials have exceptional physicochemical characteristics, including increased intestinal absorption, biodistribution, bioavailability, and improved antimicrobial and catalytic properties. Although nanotechnology is gaining ground in animal management, husbandry, and production, its wide use is still hampered by occasional toxicity and side effects. Zinc oxide nanoparticles (ZnO-NPs) have long been utilized in animal production, aquaculture, and pet animal medicine. However, the use ZnO-NPs in animals has been associated with reports of toxicity and side effects. ZnO-NPs may have shown numerous beneficial effects in animals; its use must be regulated with care to avoid unwanted consequences. Thus, this review emphasizes the usage of ZnO-NPs in animal production and laboratory animals and the potential side effects associated with the use of nanoparticles as a feed supplement and therapeutic compound.
纳米技术是一项具有广泛应用前景的深远技术，包括在普通医学、兽医医学、农业、水产养殖和食品生产等各个领域。纳米材料具有特殊的物理化学特性，包括增加肠道吸收、生物分布、生物利用度以及提高抗菌和催化性能。尽管纳米技术在动物管理、畜牧业和生产中得到了广泛应用，但由于偶尔出现的毒性和副作用，其广泛应用仍受到阻碍。氧化锌纳米颗粒（ZnO-NPs）长期以来一直用于动物生产、水产养殖和宠物动物医学。然而，ZnO-NPs 在动物中的应用与毒性和副作用的报告有关。ZnO-NPs 可能在动物中表现出许多有益的效果，但必须谨慎使用以避免产生不良后果。因此，本综述强调了 ZnO-NPs 在动物生产和实验动物中的应用，以及将纳米颗粒作为饲料补充剂和治疗化合物使用时可能产生的潜在副作用。
