乳糖抑制蛋白（lacI）基因序列。

Sequence of the lacI gene.

作者信息

Farabaugh P J

出版信息

Nature. 1978 Aug 24;274(5673):765-9. doi: 10.1038/274765a0.

Abstract

The structural gene for the lac repressor of Escherichia coli, the lacI gene has been sequenced. This 1,080 base pair region of the E. coli chromosome codes for the lac repressor protein of 360 amino acids. The DNA sequence largely confirms but extends the previously reported protein sequence and allows a structural analysis of genetic phenomena.

摘要

大肠杆菌乳糖阻遏物的结构基因，即lacI基因，已被测序。大肠杆菌染色体上这个1080个碱基对的区域编码360个氨基酸的乳糖阻遏蛋白。该DNA序列在很大程度上证实了之前报道的蛋白质序列，但对其进行了扩展，并使得对遗传现象进行结构分析成为可能。