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应用增强型跨诊断认知行为治疗对有心境或精神病谱系障碍的青少年的疗效

App-enhanced transdiagnostic CBT for adolescents with mood or psychotic spectrum disorders.

机构信息

Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.

Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA.

出版信息

J Affect Disord. 2022 Aug 15;311:319-326. doi: 10.1016/j.jad.2022.05.094. Epub 2022 May 18.

Abstract

BACKGROUND

Although transdiagnostic forms of cognitive-behavioral therapy (CBT) have been evaluated in individuals with depressive and anxiety disorders, few studies have examined their suitability for more severe disorders, such as recurrent or persistent major depressive disorder, bipolar disorder, or psychotic spectrum disorders. This study examined the acceptability and initial efficacy of an app-enhanced Unified Protocol for Adolescents [UP-A] when including youth with more severe mood disorders or psychotic spectrum disorders.

METHODS

We first adapted a mobile application (app), based on user-centered feedback from adolescents and their parents, to assist participants in reviewing session content, practicing skills learned in previous treatment sessions, and monitoring symptomatic progress. A total of 24 adolescents (M age = 15.2 years, SD = 1.6) with mood or psychotic spectrum disorders and their parents then participated in an open trial of the app-enhanced group treatment given over 9 weekly sessions.

RESULTS

Adolescent participants and their parents rated the group treatment and mobile app as acceptable and useful. We observed significant improvements over the 9-week treatment in adolescents' depressive symptoms, attenuated psychotic symptoms, and global functioning. The frequency with which adolescents used the mobile app between sessions was positively related to symptomatic and functional gains.

CONCLUSIONS

Initial findings suggest the acceptability and feasibility of a mobile app that enabled adolescent participants and their parents to review session content and practice treatment skills. Findings also indicated improvements in psychiatric and functional outcomes among the adolescent participants over the course of the app-enhanced treatment. Randomized clinical trials are needed to evaluate the efficacy of app-enhanced CBT in improving symptoms and functioning in adolescents with mood or psychotic spectrum disorders.

摘要

背景

虽然跨诊断形式的认知行为疗法(CBT)已经在抑郁和焦虑障碍患者中进行了评估,但很少有研究考察其在更严重的疾病中的适用性,例如复发性或持续性重度抑郁症、双相情感障碍或精神病谱系障碍。本研究考察了在包括患有更严重情绪障碍或精神病谱系障碍的青少年时,增强型青少年统一方案(UP-A)的可接受性和初步疗效。

方法

我们首先根据青少年及其父母的以用户为中心的反馈,对移动应用程序(app)进行了改编,以帮助参与者复习课程内容、练习在前几轮治疗中学到的技能,并监测症状进展。共有 24 名患有情绪或精神病谱系障碍的青少年(M 年龄= 15.2 岁,SD= 1.6)及其父母参加了为期 9 周的增强型团体治疗的开放试验。

结果

青少年参与者及其父母对团体治疗和移动应用程序的评价是可接受的和有用的。我们观察到在 9 周的治疗过程中,青少年的抑郁症状、减弱的精神病症状和整体功能都有显著改善。青少年在治疗期间使用移动应用程序的频率与症状和功能的改善呈正相关。

结论

初步结果表明,一种能够使青少年参与者及其父母复习课程内容和练习治疗技能的移动应用程序具有可接受性和可行性。研究结果还表明,在增强型应用程序治疗过程中,青少年参与者的心理健康和功能结果有所改善。需要进行随机临床试验来评估应用程序增强型 CBT 在改善情绪或精神病谱系障碍青少年的症状和功能方面的疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f69/9728252/a71de342b72b/nihms-1852224-f0001.jpg

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