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蓖麻对山羊的神经和胃肠道表现的自发性中毒。

Neurological and gastrointestinal manifestations of spontaneous poisoning by Ricinus communis in goats.

机构信息

Instituto Nacional de Investigación Agropecuaria, Plataforma de Salud Animal, Estación Experimental INIA Tacuarembó, Tacuarembó, Uruguay.

Department of Veterinary Clinics and Surgery, Veterinary College, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

出版信息

Toxicon. 2022 Jul 30;214:74-77. doi: 10.1016/j.toxicon.2022.05.004. Epub 2022 May 20.

Abstract

An outbreak of Ricinus communis poisoning in goats with neurological and digestive changes was related to the ingestion of different vegetative parts of the plant. Two poisoned animals died within 5 h of the plant intake showing necrotic gastroenteritis and hepatocytes degeneration and necrosis. Toxicological analysis by HPLC-DAD assay demonstrated 21.1-25.1 μg/g of ricinine in samples of ruminal fluids and 10.1-10.9 μg/g in the liver of poisoned goats.

摘要

一起蓖麻中毒事件导致山羊出现神经和消化变化,与摄入不同的植物营养部分有关。两只中毒动物在摄入植物后 5 小时内死亡,表现出坏死性肠炎和肝细胞变性和坏死。通过 HPLC-DAD 分析的毒理学分析表明,瘤胃液样品中的蓖麻毒素含量为 21.1-25.1μg/g,中毒山羊肝脏中的含量为 10.1-10.9μg/g。

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