神经胶质细胞对脊髓损伤作出反应。
The Glial Cells Respond to Spinal Cord Injury.
作者信息
Wang Ruideng, Zhou Rubing, Chen Zhengyang, Gao Shan, Zhou Fang
机构信息
Department of Orthopedics, Peking University Third Hospital, Beijing, China.
出版信息
Front Neurol. 2022 May 6;13:844497. doi: 10.3389/fneur.2022.844497. eCollection 2022.
Abstract
It is been over 100 years since glial cells were discovered by Virchow. Since then, a great deal of research was carried out to specify these further roles and properties of glial cells in central nervous system (CNS). As it is well-known that glial cells, such as astrocytes, microglia, oligodendrocytes (OLs), and oligodendrocyte progenitor cells (OPCs) play an important role in supporting and enabling the effective nervous system function in CNS. After spinal cord injury (SCI), these glial cells play different roles in SCI and repair. In this review, we will discuss in detail about the role of glial cells in the healthy CNS and how they respond to SCI.
摘要
自维尔肖发现神经胶质细胞以来，已经过去了100多年。从那时起，人们进行了大量研究，以进一步明确这些神经胶质细胞在中枢神经系统（CNS）中的作用和特性。众所周知，神经胶质细胞，如星形胶质细胞、小胶质细胞、少突胶质细胞（OLs）和少突胶质前体细胞（OPCs），在支持和实现中枢神经系统有效的神经功能方面发挥着重要作用。脊髓损伤（SCI）后，这些神经胶质细胞在脊髓损伤和修复中发挥着不同的作用。在这篇综述中，我们将详细讨论神经胶质细胞在健康中枢神经系统中的作用以及它们对脊髓损伤的反应。
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