Salazar Bruno, Ortiz Aurelio, Keswani Chetan, Minkina Tatiana, Mandzhieva Saglara, Pratap Singh Satyendra, Rekadwad Bhagwan, Borriss Rainer, Jain Akansha, Singh Harikesh B, Sansinenea Estibaliz
Facultad De Ciencias Químicas, Benemérita Universidad Autónoma De Puebla, 72590, Puebla, Pue, México.
Academy of Biology and Biotechnology, Southern Federal University, Rostov-on-Don, 344006, Russia.
Microb Ecol. 2023 Jul;86(1):1-24. doi: 10.1007/s00248-022-02044-2. Epub 2022 May 23.
Several fungi act as parasites for crops causing huge annual crop losses at both pre- and post-harvest stages. For years, chemical fungicides were the solution; however, their wide use has caused environmental contamination and human health problems. For this reason, the use of biofungicides has been in practice as a green solution against fungal phytopathogens. In the context of a more sustainable agriculture, microbial biofungicides have the largest share among the commercial biocontrol products that are available in the market. Precisely, the genus Bacillus has been largely studied for the management of plant pathogenic fungi because they offer a chemically diverse arsenal of antifungal secondary metabolites, which have spawned a heightened industrial engrossment of it as a biopesticide. In this sense, it is indispensable to know the wide arsenal that Bacillus genus has to apply these products for sustainable agriculture. Having this idea in our minds, in this review, secondary metabolites from Bacillus having antifungal activity are chemically and structurally described giving details of their action against several phytopathogens. Knowing the current status of Bacillus secreted antifungals is the base for the goal to apply these in agriculture and it is addressed in depth in the second part of this review.
几种真菌作为农作物的寄生虫，在收获前和收获后阶段都会导致每年巨大的作物损失。多年来，化学杀菌剂一直是解决方案；然而，它们的广泛使用已造成环境污染和人类健康问题。因此，生物杀菌剂的使用已成为对抗真菌植物病原体的绿色解决方案。在更可持续农业的背景下，微生物生物杀菌剂在市场上现有的商业生物防治产品中占比最大。确切地说，芽孢杆菌属已被广泛研究用于管理植物病原真菌，因为它们提供了化学性质多样的抗真菌次生代谢产物库，这引发了该属作为生物农药在工业上的高度关注。从这个意义上说，了解芽孢杆菌属所拥有的广泛物质库对于将这些产品应用于可持续农业至关重要。基于这个想法，在本综述中，对具有抗真菌活性的芽孢杆菌次生代谢产物进行了化学和结构描述，并详细说明了它们对几种植物病原体的作用。了解芽孢杆菌分泌的抗真菌剂的现状是将其应用于农业这一目标的基础，本综述的第二部分对此进行了深入探讨。
