人乳牙干细胞对临床疾病的治疗作用：一项叙述性综述研究。
The therapeutic effects of stem cells from human exfoliated deciduous teeth on clinical diseases: a narrative review study.
作者信息
Naderi Fariba, Mehdiabadi Mohsen, Kamarehei Farideh
机构信息
Pediatric Dentistry Department, Faculty of Dentistry, Hamadan University of Medical Sciences Hamadan, Iran.
Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences Hamadan, Iran.
出版信息
Am J Stem Cells. 2022 Apr 25;11(2):28-36. eCollection 2022.
INTRODUCTION
Stem cells isolated from human dental pulp tissue are different from other sources of Mesenchymal stem cells because of their embryonic neural crest sources and neuro-trophic potential. These stem cells consist of dental pulp stem cells from human permanent teeth and stem cells from human exfoliated deciduous teeth.
AIM
In this study, we survey the advantages and disadvantages of these stem cells with therapies attitude.
MAIN TEXT
Stem cells from human exfoliated deciduous teeth with a high proliferation rate could distinguish into a wide types of cells. After stem cell banking appearance, stem cells from human exfoliated deciduous teeth can preserve and use for treatment, especially in regenerative medicine. But the crucial health hazards related to stem cell transplantation, such as immune rejection reactions and the interaction with other tissues, should not be neglected.
CONCLUSION
Further experiments are required to approve the impact of these stem cells on different human disorders.
引言
从人牙髓组织中分离出的干细胞因其胚胎神经嵴来源和神经营养潜能，不同于其他来源的间充质干细胞。这些干细胞包括来自人恒牙的牙髓干细胞和来自人脱落乳牙的干细胞。
目的
在本研究中，我们从治疗角度审视这些干细胞的优缺点。
正文
人脱落乳牙干细胞增殖率高，可分化为多种类型的细胞。干细胞库出现后，人脱落乳牙干细胞可保存并用于治疗，尤其是在再生医学中。但与干细胞移植相关的重大健康风险，如免疫排斥反应以及与其他组织的相互作用，不应被忽视。
结论
需要进一步实验来证实这些干细胞对不同人类疾病的影响。
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