Department of Cardiology, Texas Heart Institute, Houston, Texas.
Department of Cardiovascular Radiology, Texas Heart Institute, Houston, Texas.
Tex Heart Inst J. 2022 May 1;49(3). doi: 10.14503/THIJ-21-7680.
Gadolinium-based contrast agents have expanded the diagnostic usefulness and capability of magnetic resonance imaging. Despite their highly favorable safety profile, these agents have been associated with nephrogenic systemic fibrosis in a small number of patients who have advanced kidney disease. Recently, trace amounts of gadolinium deposition in the brain and other organs have been reported after contrast exposure, even in patients with normal renal function. In this review, we provide a brief overview of recent updates and discuss typical clinical situations related to the use of gadolinium-based contrast agents.
钆基造影剂扩展了磁共振成像的诊断用途和能力。尽管这些造影剂具有非常良好的安全性，但在少数患有晚期肾病的患者中，它们与肾源性系统性纤维化有关。最近，即使在肾功能正常的患者中，也有报道称在造影剂暴露后，大脑和其他器官中会有微量的钆沉积。在这篇综述中，我们提供了最新进展的简要概述，并讨论了与使用钆基造影剂相关的典型临床情况。
