一种基于半花菁的近红外荧光探针，可在完全水相介质中用于气相肼的检测和生物成像。
A hemicyanine-based near-infrared fluorescent probe for vapor-phase hydrazine detection and bioimaging in a complete aqueous media.
机构信息
Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China; College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Oct 15;279:121406. doi: 10.1016/j.saa.2022.121406. Epub 2022 May 18.
A novel near-infrared fluorescent probe CyOE based on hemicyanine dye containing acetyl as a recognition site is reported. The probe CyOE shows high selectivity and sensitivity (LOD = 82 nM, 2.58 ppb), as well as good water solubility and quantitative detectability of hydrazine in the concentration range of 0-75 μM (R = 0.993). Moreover, CyOE has a significant increase in fluorescence at 735 nm with the addition of NH, which provides a rapid, colorimetric and gas-phase detection method for NH in both aqueous solution and real water samples. In addition, CyOE is successfully utilized to visualize hydrazine in cells with low cytotoxicity and high cell permeability.
一种基于半花菁染料的新型近红外荧光探针 CyOE 被报道，该探针含有乙酰基作为识别位点。探针 CyOE 表现出高选择性和灵敏度（LOD=82 nM，2.58 ppb），以及良好的水溶性和肼在 0-75 μM 浓度范围内的定量检测能力（R=0.993）。此外，CyOE 在加入 NH 时在 735nm 处的荧光显著增加，这为水溶液和实际水样中的 NH 提供了一种快速、比色和气相检测方法。此外，CyOE 成功地用于可视化细胞内低细胞毒性和高细胞通透性的肼。
Zotero 插件