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纳米药物递送系统的新进展:与胃癌

New Advances in Nano-Drug Delivery Systems: and Gastric Cancer.

作者信息

Zhu Xiang, Su Tingting, Wang Shouhua, Zhou Huiqing, Shi Weibin

机构信息

Department of General Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Front Oncol. 2022 May 10;12:834934. doi: 10.3389/fonc.2022.834934. eCollection 2022.

Abstract

With the development of materials science and biomedicine, the application of nanomaterials in the medical field is further promoted. In the process of the diagnosis and treatment of diseases, a variety of drugs need to be used. It is an ideal state to make these drugs arrive at a specific location at a specific time and release at a specific speed, which can improve the bioavailability of drugs and reduce the adverse effects of drugs on normal tissues. Traditional drug delivery methods such as tablets, capsules, syrups, and ointments have certain limitations. The emergence of a new nano-drug delivery system further improves the accuracy of drug delivery and the efficacy of drugs. It is well known that the development of the cancer of the stomach is the most serious consequence for the infection of . For the patients who are suffering from gastric cancer, the treatments are mainly surgery, chemotherapy, targeted and immune therapy, and other comprehensive treatments. Although great progress has been made, the diagnosis and prognosis of gastric cancer are still poor with patients usually diagnosed with cancer at an advanced stage. Current treatments are of limited benefits for patients, resulting in a poor 5-year survival rate. Nanomaterials may play a critical role in early diagnosis. A nano-drug delivery system can significantly improve the chemotherapy, targeted therapy, and immunotherapy of advanced gastric cancer, reduce the side effects of the original treatment plan and provide patients with better benefits. It is a promising treatment for gastric cancer. This article introduces the application of nanomaterials in the diagnosis and treatment of and gastric cancer.

摘要

随着材料科学和生物医学的发展,纳米材料在医学领域的应用得到进一步推动。在疾病的诊断和治疗过程中,需要使用多种药物。使这些药物在特定时间到达特定位置并以特定速度释放,这是一种理想状态,这样可以提高药物的生物利用度并减少药物对正常组织的不良反应。传统的药物递送方法,如片剂、胶囊、糖浆和软膏等,存在一定的局限性。新型纳米药物递送系统的出现进一步提高了药物递送的准确性和药物的疗效。众所周知,胃癌的发展是感染的最严重后果。对于胃癌患者,治疗方法主要是手术、化疗、靶向和免疫治疗等综合治疗。尽管已经取得了很大进展,但胃癌的诊断和预后仍然很差,患者通常在晚期才被诊断出患有癌症。目前的治疗方法对患者的益处有限,导致5年生存率较低。纳米材料可能在早期诊断中发挥关键作用。纳米药物递送系统可以显著改善晚期胃癌的化疗、靶向治疗和免疫治疗,减少原治疗方案的副作用,并为患者带来更好的益处。这是一种很有前景的胃癌治疗方法。本文介绍了纳米材料在胃癌诊断和治疗中的应用。

相似文献

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New Advances in Nano-Drug Delivery Systems: and Gastric Cancer.纳米药物递送系统的新进展:与胃癌
Front Oncol. 2022 May 10;12:834934. doi: 10.3389/fonc.2022.834934. eCollection 2022.

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