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同侧复发性耳廓黑色素瘤切除术后转移性默克尔细胞癌的发生

Development of metastatic Merkel cell carcinoma following the excision of same-sided recurrent auricular melanoma.

作者信息

Cartwright Jake K, Snyder Daniel H, Moreno Francisco G

机构信息

Quillen College of Medicine East Tennessee State University Mountain Home Tennessee USA.

Knoxville FNA Clinic Knoxville Tennessee USA.

出版信息

Clin Case Rep. 2022 May 22;10(5):e05891. doi: 10.1002/ccr3.5891. eCollection 2022 May.

DOI:10.1002/ccr3.5891
PMID:35620264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9124612/
Abstract

Merkel cell carcinoma (MCC) is a rare neuroendocrine malignancy of the skin that is highly aggressive and often metastasizes early. MCC is diagnosed based on histopathological findings and is most commonly treated with surgical resection, which may be accompanied by chemotherapy and/or radiation. This report describes a 55-year-old male patient with the history of recurrent malignant melanoma of the right pinna and subsequent excision. Three years following the excision of melanoma, he presented with a lesion to the right forehead as well as a right-sided neck mass that were found to be metastatic Merkel cell carcinoma.

摘要

默克尔细胞癌(MCC)是一种罕见的皮肤神经内分泌恶性肿瘤,具有高度侵袭性,且常早期发生转移。MCC依据组织病理学检查结果进行诊断,最常用手术切除治疗,可能还会辅以化疗和/或放疗。本报告描述了一名55岁男性患者,有右耳廓复发性恶性黑色素瘤病史并随后接受了切除手术。黑色素瘤切除术后三年,他右侧前额出现一处病灶以及右侧颈部肿块,经检查发现为转移性默克尔细胞癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/38831dd9541c/CCR3-10-e05891-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/50e287f134aa/CCR3-10-e05891-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/8748ff8d32e3/CCR3-10-e05891-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/38831dd9541c/CCR3-10-e05891-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/50e287f134aa/CCR3-10-e05891-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/8748ff8d32e3/CCR3-10-e05891-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0559/9124612/38831dd9541c/CCR3-10-e05891-g003.jpg

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本文引用的文献

1
Merkel Cell Carcinoma: Evaluation of the Clinico-Pathological Characteristics, Treatment Strategies and Prognostic Factors in a Monocentric Retrospective Series (n=143).Merkel细胞癌:单中心回顾性系列研究(n = 143)中临床病理特征、治疗策略及预后因素的评估
Front Oncol. 2021 Dec 17;11:737842. doi: 10.3389/fonc.2021.737842. eCollection 2021.
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Metastatic Merkel cell carcinoma and malignant melanoma in a single sentinel lymph node.单个前哨淋巴结中的转移性默克尔细胞癌和恶性黑色素瘤。
SAGE Open Med Case Rep. 2021 Jun 16;9:2050313X211023685. doi: 10.1177/2050313X211023685. eCollection 2021.
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Molecular Profiling of Merkel Cell Polyomavirus-Associated Merkel Cell Carcinoma and Cutaneous Melanoma.
默克尔细胞多瘤病毒相关默克尔细胞癌和皮肤黑色素瘤的分子剖析
Diagnostics (Basel). 2021 Feb 1;11(2):212. doi: 10.3390/diagnostics11020212.
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Merkel cell carcinoma: A review. Merkel 细胞癌:综述。
J Cutan Pathol. 2021 Mar;48(3):411-421. doi: 10.1111/cup.13910. Epub 2020 Dec 3.
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Malignant melanoma after treatment for Merkel cell carcinoma.默克尔细胞癌治疗后发生的恶性黑色素瘤。
An Bras Dermatol. 2020 Sep-Oct;95(5):662-664. doi: 10.1016/j.abd.2020.02.013. Epub 2020 Jul 15.
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Management Recommendations for Merkel Cell Carcinoma-A Danish Perspective.默克尔细胞癌的管理建议——丹麦视角
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Merkel cell carcinoma.默克尔细胞癌。
Nat Rev Dis Primers. 2017 Oct 26;3:17077. doi: 10.1038/nrdp.2017.77.
9
Understanding the influence of patient demographics on disease severity, treatment strategy, and survival outcomes in merkel cell carcinoma: a surveillance, epidemiology, and end-results study.了解患者人口统计学特征对默克尔细胞癌疾病严重程度、治疗策略和生存结果的影响:一项监测、流行病学和最终结果研究。
Oncoscience. 2017 Sep 14;4(7-8):106-114. doi: 10.18632/oncoscience.358. eCollection 2017 Jul.
10
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J Skin Cancer. 2014;2014:184245. doi: 10.1155/2014/184245. Epub 2014 Dec 10.