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新型冠状病毒肺炎引发的周围神经病变:治疗新视角

Peripheral Neuropathies Derived from COVID-19: New Perspectives for Treatment.

作者信息

Córdova-Martínez Alfredo, Caballero-García Alberto, Pérez-Valdecantos Daniel, Roche Enrique, Noriega-González David César

机构信息

Department of Biochemistry, Molecular Biology and Physiology, Faculty of Health Sciences, GIR Physical Exercise and Aging, University of Valladolid, Campus Duques de Soria, 42004 Soria, Spain.

Department of Anatomy and Radiology, Faculty of Health Sciences, GIR Physical Exercise and Aging, University of Valladolid, Campus Duques de Soria, 42004 Soria, Spain.

出版信息

Biomedicines. 2022 May 2;10(5):1051. doi: 10.3390/biomedicines10051051.

Abstract

Peripheral neuropathies constitute a group of disorders affecting the peripheral nervous system. Neuropathies have multiple causes such as infections (i.e., COVID-19), diabetes, and nutritional (low vitamin levels), among others. Many micronutrients, such as vitamins (A, C, D, E, B6, B12, and folate), certain minerals (Fe, Mg, Zn, Se, and Cu), and ω-3 fatty acids have immunomodulatory effects. Therefore, they may play an instrumental role in the treatment of COVID-19 infection. However, many COVID-19 patients can undergo neuropathy. In this context, there is a wealth of information on a variety of first-, second-, and third-line treatment options. This review focuses on the application of nutraceutical strategies in order to improve the symptomatology of neuropathy and neuropathic pain in patients that suffered from COVID-19. Our aim is to provide an alternative vision to traditional medical-pharmacological treatment through nutraceuticals.

摘要

周围神经病变是一组影响周围神经系统的疾病。神经病变有多种病因,如感染(即新冠病毒病)、糖尿病和营养缺乏(维生素水平低)等。许多微量营养素,如维生素(A、C、D、E、B6、B12和叶酸)、某些矿物质(铁、镁、锌、硒和铜)以及ω-3脂肪酸具有免疫调节作用。因此,它们可能在新冠病毒病感染的治疗中发挥重要作用。然而,许多新冠病毒病患者会出现神经病变。在此背景下,有大量关于各种一线、二线和三线治疗方案的信息。本综述聚焦于营养补充策略的应用,以改善新冠病毒病患者的神经病变症状和神经性疼痛。我们的目的是通过营养补充剂为传统医学 - 药理学治疗提供另一种视角。

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