Migliorini Filippo, Maffulli Nicola, Cuozzo Francesco, Elsner Karen, Hildebrand Frank, Eschweiler Jörg, Driessen Arne
Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Hospital, 52074 Aachen, Germany.
Department of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Italy.
J Clin Med. 2022 May 17;11(10):2837. doi: 10.3390/jcm11102837.
Whether mobile-bearing (MB) unicompartmental knee arthroplasty (UKA) performs better than fixed-bearing (FB) implants in patients with monocompartmental osteoarthritis (OA) still remains unclear. Therefore, a meta-analysis comparing MB versus FB for UKA was conducted to investigate the possible advantages of MB versus FB in patient-reported outcome measures (PROMs), range of motion (ROM), and complications. We hypothesised that the MB design performs better than FB.
This systematic review was conducted according to the 2020 PRISMA guidelines. In December 2021, PubMed, Web of Science, Google Scholar, and Embase were accessed, with no time constraints. All the clinical investigations comparing MB versus FB bearing for UKA were accessed. Only studies published in peer-reviewed journals were considered. Studies reporting data on revision settings were excluded, as were those combining unicompartmental and total knee arthroplasty.
Data from 25 studies (4696 patients) were collected; 58% (2724 of 4696 patients) were women. The mean length of follow-up was 45.8 ± 43.2. The mean age of the patients was 65.0 ± 5.6 years. No difference was found in range of motion ( = 0.05), Knee Scoring System ( = 0.9), function subscale ( = 0.2), and Oxford Knee Score ( = 0.4). No difference was found in the rate of revision ( = 0.2), aseptic loosening ( = 0.9), deep infections ( = 0.99), fractures ( = 0.6), and further extension of OA to the contralateral joint compartment ( = 0.2).
The present meta-analysis failed to identify the possible superiority of the MB implants over the FB for UKA in patients with monocompartmental knee osteoarthritis. Long observational investigations are required to evaluate possible long-term complications and implant survivorship. These results should be interpreted within the limitations of the present study.
在单髁骨关节炎(OA)患者中,活动平台(MB)单髁膝关节置换术(UKA)是否比固定平台(FB)植入物表现更好仍不清楚。因此,进行了一项比较MB与FB用于UKA的荟萃分析,以研究MB相对于FB在患者报告结局指标(PROMs)、活动范围(ROM)和并发症方面可能存在的优势。我们假设MB设计比FB表现更好。
本系统评价按照2020年PRISMA指南进行。2021年12月,检索了PubMed、科学网、谷歌学术和Embase,无时间限制。纳入了所有比较MB与FB用于UKA的临床研究。仅考虑发表在同行评审期刊上的研究。排除报告翻修情况数据的研究,以及那些将单髁膝关节置换术和全膝关节置换术相结合的研究。
收集了25项研究(4696例患者)的数据;58%(4696例患者中的2724例)为女性。平均随访时间为45.8±43.2。患者的平均年龄为65.0±5.6岁。在活动范围(P = 0.05)、膝关节评分系统(P = 0.9)、功能子量表(P = 0.2)和牛津膝关节评分(P = 0.4)方面未发现差异。在翻修率(P = 0.2)、无菌性松动(P = 0.9)、深部感染(P = 0.99)、骨折(P = 0.6)以及OA向对侧关节腔进一步扩展(P = 0.2)方面未发现差异。
本荟萃分析未能确定在单髁膝关节骨关节炎患者中,MB植入物相对于FB用于UKA可能具有的优越性。需要长期观察性研究来评估可能的长期并发症和植入物生存率。这些结果应在本研究的局限性内进行解读。