Marmiroli Marta, Marmiroli Nelson, Pagano Luca
Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43124 Parma, Italy.
Consorzio Interuniversitario Nazionale per le Scienze Ambientali (CINSA), Parco Area delle Scienze 11/A, 43124 Parma, Italy.
Nanomaterials (Basel). 2022 May 12;12(10):1658. doi: 10.3390/nano12101658.
In recent years, plant-nanomaterial interactions have been studied, highlighting their effects at physiological and molecular levels. Transcriptomics and proteomics studies have shown pathways and targets of nanomaterial exposure and plant response, with particular regard to abiotic stress and oxidative stress. Only little information has been reported on engineered nanomaterial (ENMs) interactions with plant genetic material, both at a genomic and organellar DNAs level. Plants can be useful experimental material, considering they both contain chloroplast and mitochondrial DNAs and several plant genomes have been completely sequenced (e.g., , , , , etc.). In this mini review, the methods and the evidence reported in the present literature concerning the level of genotoxicity induced by ENMs exposure have been considered. Consolidated and potential strategies, which can be applied to assess the nanomaterial genotoxicity in plants, are reviewed.
近年来,人们对植物与纳米材料的相互作用进行了研究,突出了它们在生理和分子水平上的影响。转录组学和蛋白质组学研究揭示了纳米材料暴露和植物响应的途径及靶点,特别是在非生物胁迫和氧化应激方面。关于工程纳米材料(ENMs)与植物遗传物质在基因组和细胞器DNA水平上的相互作用,目前报道的信息很少。考虑到植物既含有叶绿体和线粒体DNA,且多个植物基因组已完成测序(如 、 、 、 等),植物可作为有用的实验材料。在本综述中,我们考虑了现有文献中报道的关于ENMs暴露诱导的遗传毒性水平的方法和证据。本文综述了可用于评估植物中纳米材料遗传毒性的成熟和潜在策略。