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免疫功能低下猫的疫苗接种。

Vaccination of Immunocompromised Cats.

机构信息

Clinic of Small Animal Medicine, Centre for Clinical Veterinary Medicine, LMU Munich, 80539 Munich, Germany.

Institute of Virology, Department for Pathobiology, University of Veterinary Medicine, 1210 Vienna, Austria.

出版信息

Viruses. 2022 Apr 28;14(5):923. doi: 10.3390/v14050923.

Abstract

Immunocompromise is a common condition in cats, especially due to widespread infections with immunosuppressive viruses, such as feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV), but also due to chronic non-infectious diseases, such as tumours, diabetes mellitus, and chronic kidney disease, as well as treatment with immunosuppressive drugs, such as glucocorticoids, cyclosporins, or tumour chemotherapy. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from eleven European countries, discusses the current knowledge and rationale for vaccination of immunocompromised cats. So far, there are few data available on vaccination of immunocompromised cats, and sometimes studies produce controversial results. Thus, this guideline summarizes the available scientific studies and fills in the gaps with expert opinion, where scientific studies are missing. Ultimately, this review aims to help veterinarians with their decision-making in how best to vaccinate immunocompromised cats.

摘要

免疫功能低下是猫的常见病症,这主要是由于猫免疫缺陷病毒(FIV)和猫白血病病毒(FeLV)等免疫抑制性病毒的广泛感染,但也与肿瘤、糖尿病和慢性肾病等慢性非传染性疾病以及免疫抑制药物(如糖皮质激素、环孢素或肿瘤化疗)的治疗有关。在这篇综述中,来自 11 个欧洲国家的猫科医学领域的科学独立专家组——欧洲猫病咨询委员会(ABCD),讨论了免疫功能低下猫疫苗接种的现有知识和基本原理。到目前为止,关于免疫功能低下猫疫苗接种的数据很少,有时研究结果也存在争议。因此,本指南总结了现有的科学研究,并在缺乏科学研究的情况下用专家意见填补了空白。最终,本综述旨在帮助兽医做出最佳决策,为免疫功能低下的猫接种疫苗。

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