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老年髋部骨折手术后发生术后肺炎的危险因素:一项系统评价和荟萃分析

Risk Factors for Postoperative Pneumonia in the Elderly Following Hip Fracture Surgery: A Systematic Review and Meta-Analysis.

作者信息

Lee Sang Hee, Kim Ki Uk

机构信息

Department of Internal Medicine, Wonkwang University Sanbon Hospital, Gunpo-si, Republic of Korea.

Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Republic of Korea.

出版信息

Geriatr Orthop Surg Rehabil. 2022 Mar 14;13:21514593221083825. doi: 10.1177/21514593221083825. eCollection 2022.

DOI:10.1177/21514593221083825
PMID:35634259
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9133882/
Abstract

Pneumonia is a serious complication following hip fracture surgery in older people. However, the prevalence and risk factors of postoperative pneumonia (POP) are not well-established. This study identified pre- and peri-operative factors associated with the development of POP following hip fracture surgery. We searched the Cochrane library, PubMed, and Embase databases for relevant articles published up to June 2021. Studies involving older patients who underwent hip fracture surgery were considered if they detailed the demographic or surgical characteristics of the participants. For all analyses, the pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. A total of 24 studies (288819 participants) were included. The overall prevalence of POP following hip fracture surgery was 5.0%. There were 36 risk factors for POP, and the meta-analysis included the five most common: delayed surgery (OR: 1.84, 95% CI: 1.29-2.63), low serum albumin (OR: 2.34, 95% CI: .82-6.73), chronic respiratory diseases (OR: 2.42, 95% CI: 1.82-3.24), increased age (OR: 1.25, 95% CI:1.11-1.40), and male sex (OR: 2.22, 95% CI: 2.00-2.47). The prevalence of POP was 5.0% following hip fracture surgery in the elderly. Older age, male sex, chronic respiratory diseases, delayed surgery, and low serum albumin were significant risk factors. Clinicians treating hip fracture patients must remain be aware of these risk factors.

摘要

肺炎是老年人髋部骨折手术后的一种严重并发症。然而,术后肺炎(POP)的患病率和危险因素尚未完全明确。本研究确定了髋部骨折手术后与POP发生相关的术前和围手术期因素。我们在Cochrane图书馆、PubMed和Embase数据库中检索了截至2021年6月发表的相关文章。如果研究详细描述了接受髋部骨折手术的老年患者的人口统计学或手术特征,则纳入该研究。对于所有分析,计算合并比值比(OR)和95%置信区间(95%CI)。共纳入24项研究(288819名参与者)。髋部骨折手术后POP的总体患病率为5.0%。POP有36个危险因素,荟萃分析纳入了最常见的5个因素:手术延迟(OR:1.84,95%CI:1.29 - 2.63)、血清白蛋白水平低(OR:2.34,95%CI:0.82 - 6.73)、慢性呼吸系统疾病(OR:2.42,95%CI:1.82 - 3.24)、年龄增加(OR:1.25,95%CI:1.11 - 1.40)和男性(OR:2.22,95%CI:2.00 - 2.47)。老年人髋部骨折手术后POP的患病率为5.0%。年龄较大、男性、慢性呼吸系统疾病、手术延迟和血清白蛋白水平低是重要的危险因素。治疗髋部骨折患者的临床医生必须注意这些危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/051bd3f8bf34/10.1177_21514593221083825-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/d84e276215e1/10.1177_21514593221083825-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/822e840425cf/10.1177_21514593221083825-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/11640acfe3ac/10.1177_21514593221083825-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/051bd3f8bf34/10.1177_21514593221083825-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/d84e276215e1/10.1177_21514593221083825-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/822e840425cf/10.1177_21514593221083825-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/11640acfe3ac/10.1177_21514593221083825-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ec2/9133882/051bd3f8bf34/10.1177_21514593221083825-fig4.jpg

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