Rashid Shazia, Bashir Faisal, Khanday Farooq A, Beigh M Rafiq
IEEE Trans Nanobioscience. 2023 Jan;22(1):192-198. doi: 10.1109/TNB.2022.3178763. Epub 2022 Dec 29.
In this paper, a novel structure of double gate tunnel FET has been proposed and simulated for biosensing applications. The device uses III-V compound semiconductors and an n+ doped pocket at the source channel junction. Biomolecules of different dielectric constants (K) with different charge densities (Nbio), both negative and positive, are inserted in the nano-gap cavities (15 nm ×1.5 nm) that have been created under gates near source channel junction to capture biomolecules. From extensive 2D simulations, ION sensitivity of 4.351 ×10/1.03 ×10/1.514 ×10 , subthreshold swing sensitivity of 15.67/20.21/18.57 mV/dec, and threshold voltage sensitivity of 18/12/23 mV for neutral (K = 12)/negatively charged biomolecules ( [Formula: see text] C/cm2, K = 12)/positively charged biomolecules ( [Formula: see text] C/cm2, K = 12) respectively has been observed. Also, transconductance sensitivity of 9.74 ×10 and ION/IOFF sensitivity of 5.255 ×10 for neutral biomolecules (K = 12) has been calculated. Furthermore, the device performance with one-third filled cavities, two-third filled cavities and fully filled cavities has also been studied. The performance of the proposed biosensor has been compared with the previously published work and it has been observed that the sensitivity of the proposed biosensor is 100 times better than the best reported biosensor.
在本文中,提出了一种用于生物传感应用的新型双栅隧道场效应晶体管结构并进行了模拟。该器件采用III-V族化合物半导体,并在源极沟道结处设置了一个n+掺杂口袋。将具有不同介电常数(K)和不同电荷密度(Nbio)(包括正负电荷)的生物分子插入在源极沟道结附近栅极下方创建的纳米间隙腔(15纳米×1.5纳米)中,以捕获生物分子。通过广泛的二维模拟,分别观察到中性(K = 12)/带负电生物分子([公式:见原文] C/cm2,K = 12)/带正电生物分子([公式:见原文] C/cm2,K = 12)的离子灵敏度为4.351×10/1.03×10/1.514×10,亚阈值摆幅灵敏度为15.67/20.21/18.57 mV/dec,阈值电压灵敏度为18/12/23 mV。此外,还计算了中性生物分子(K = 12)的跨导灵敏度为9.74×10和离子导通/截止灵敏度为5.255×10。此外,还研究了腔体填充三分之一、三分之二和完全填充时的器件性能。将所提出的生物传感器的性能与先前发表的工作进行了比较,发现所提出的生物传感器的灵敏度比报道的最佳生物传感器高100倍。