Torres-Villaros Héloïse, Louis-Philippe Steven, Amari Fatima, Giocanti-Aurégan Audrey, Janicot Lucie
Department of Ophthalmology, Avicenne Hospital, 125, rue de Stalingrad, 93000, Bobigny, France.
Am J Ophthalmol Case Rep. 2022 May 18;27:101588. doi: 10.1016/j.ajoc.2022.101588. eCollection 2022 Sep.
To describe the first reported case of outer retinal damage following the use of Membrane Blue Dual for epiretinal membrane (ERM) surgery.
A 74-year-old female underwent pars plana vitrectomy and ERM peeling assisted with Membrane Blue Dual for an idiopathic ERM. Postoperatively, the patient reported a decline in visual acuity with a central scotoma. Fundus examination revealed a well-defined retinal whitening in the peeling area which evolved into pigmentary changes as confirmed by fundus autofluorescence. Optical coherence tomography (OCT) showed loss of outer retinal layers and irregular mottling of the retinal pigment epithelium. Fundus and OCT appearance remained unchanged after 4 months and the central scotoma also persisted.
ERM surgery assisted with Membrane Blue Dual can induce major changes in retinal pigment epithelium and outer retinal layers. This adverse event which probably results from combined light and dye toxicity should be considered by all surgeons even though its occurrence is rare.
描述首例报道的在使用双波长膜蓝进行视网膜前膜（ERM）手术之后出现的外层视网膜损伤病例。
一名74岁女性因特发性ERM接受了玻璃体切除术及使用双波长膜蓝辅助的ERM剥除术。术后，患者报告视力下降并伴有中心暗点。眼底检查发现剥除区域有边界清晰的视网膜变白，经眼底自发荧光证实其演变为色素改变。光学相干断层扫描（OCT）显示外层视网膜层缺失以及视网膜色素上皮不规则斑驳。4个月后眼底和OCT表现未变，中心暗点也持续存在。
双波长膜蓝辅助的ERM手术可引起视网膜色素上皮和外层视网膜层的重大变化。尽管这种不良事件很少发生，但所有外科医生都应考虑到这可能是由光和染料的联合毒性导致的。
