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视网膜前膜切除术后推测的复方亮蓝G和Endolight诱导的黄斑损伤

Presumed Combined Brilliant Blue G and Endolight-Induced Macular Damage following Epiretinal Membrane Removal Surgery.

作者信息

Venkatesh Ramesh, Gupta Aditi, Yadav Naresh Kumar, Chhablani Jay

机构信息

Department of Retina and Vitreous, Narayana Nethralaya, Bengaluru, Karnataka, India.

Department of Retina and Vitreous, University of Pittsburgh School of Medicine, Medical Retina and Vitreoretinal Surgery, Pittsburgh, PA, USA.

出版信息

J Curr Ophthalmol. 2022 Jul 26;34(2):267-270. doi: 10.4103/joco.joco_46_22. eCollection 2022 Apr-Jun.

Abstract

PURPOSE

To report a rare case of macular outer retinal and retinal pigment epithelium (RPE) damage following brilliant blue G (BBG)-assisted epiretinal membrane (ERM) removal surgery.

METHODS

Retrospective, observational case report.

RESULTS

An 85-year-old lady presented with decreased vision in the left eye and a best-corrected visual acuity of 20/400. The right eye examination was within normal limits. The left eye had a significant cataract, and the fundus examination through the cataractous haze showed an ERM with macular pucker, which was confirmed on an optical coherence tomography (OCT) scan. A combined cataract surgery with intraocular lens implantation and BBG-assisted ERM removal and internal limiting membrane peeling surgery was performed. Over the subsequent visits, a well-defined area of outer retinal and RPE alteration was identified on OCT and fundus autofluorescence without significant improvement in visual acuity. At the last follow-up visit, the visual acuity minimally improved to 20/200.

CONCLUSIONS

Macular toxicity due to repeated usage of BBG dye and high intensity focal endo-illumination may lead to poor visual outcome following ERM removal or similar macular surgeries. Adequate precautions need to be taken to prevent vision loss.

摘要

目的

报告1例在亮蓝G(BBG)辅助下视网膜前膜(ERM)切除术后黄斑区外层视网膜和视网膜色素上皮(RPE)损伤的罕见病例。

方法

回顾性观察病例报告。

结果

一位85岁女性因左眼视力下降就诊,最佳矫正视力为20/400。右眼检查正常。左眼有明显白内障,透过白内障混浊进行眼底检查显示有伴有黄斑皱缩的ERM,光学相干断层扫描(OCT)证实了这一点。进行了白内障摘除联合人工晶状体植入术以及BBG辅助的ERM切除术和内界膜剥除术。在随后的随访中,OCT和眼底自发荧光检查发现外层视网膜和RPE有明确的改变区域,视力无明显改善。在最后一次随访时,视力稍有改善,达到20/200。

结论

重复使用BBG染料和高强度聚焦眼内照明导致的黄斑毒性可能会导致ERM切除或类似黄斑手术术后视力不佳。需要采取充分的预防措施以防止视力丧失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/19cc/9487014/b6b196b1f86b/JCO-34-267-g001.jpg

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