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加尔各答-考文垂急性心力衰竭对比注册研究:观察公共、私人和全民健康系统对中低收入城市患者结局的影响(KOLCOV HF 研究)。

Kolkata-Coventry comparative registry study of acute heart failure: an insight into the impact of public, private and universal health systems on patient outcomes in low-middle income cities (KOLCOV HF Study).

机构信息

Department of Cardiology, Apollo Gleneagles Hospital, Kolkata, West Bengal, India.

Department of Cardiology, Nilratan Sircar Medical College and Hospital, Kolkata, West Bengal, India.

出版信息

Open Heart. 2022 May;9(1). doi: 10.1136/openhrt-2022-001964.

Abstract

INTRODUCTION

Survival gaps in acute heart failure (AHF) continue to expand globally. Multinational heart failure (HF) registries have highlighted variations between countries. Whether discrepancies in HF practice and outcomes occur across different health systems (ie, private, public or universal healthcare) within a city or between countries remain unclear. Insight into organisational care is also scarce. With increasing public scrutiny of health inequalities, a study to address these limitations is timely.

METHOD

KOLCOV-HF study prospectively compared patients with AHF in public (Nil Ratan Sircar Hospital (NRS)) versus private (Apollo Gleneagles Hospital (AGH)) hospitals of Kolkata, India, and one with universal health coverage in a socioeconomically comparable city of Coventry, England (University Hospitals Coventry & Warwickshire (UHCW)). Data variables were adapted from UK's National HF Audit programme, collected over 24 months. Predictors of in-hospital mortality and length of hospitalisation were assessed for each centre.

RESULTS

Among 1652 patients, in-hospital mortality was highest in government-funded NRS (11.9%) while 3 miles north, AGH had significantly lower mortality (7.5%, p=0.034), similar to UHCW (8%). This could be attributed to distinct HF phenotypes and differences in clinical and organisational care. As expected, low blood pressure was associated with a significantly greater risk of death in patients served by public hospitals UHCW and NRS.

CONCLUSION

Marked differences in HF characteristics, management and outcomes exist intra-regionally, and between low-middle versus high-income countries across private, public and universal healthcare systems. Physicians and policymakers should take caution when applying country-level data locally when developing strategies to address local evidence-practice gaps in HF.

摘要

简介

急性心力衰竭(AHF)患者的生存率在全球范围内仍持续存在差距。多国心力衰竭(HF)注册研究强调了各国之间的差异。在一个城市或国家之间,不同医疗体系(即私人、公共或全民医保)内的 HF 实践和结果是否存在差异仍不清楚。对组织护理的了解也很有限。随着公众对健康不平等的关注度不断提高,及时开展这项研究具有重要意义。

方法

KOLCOV-HF 研究前瞻性比较了印度加尔各答市公立(Nil Ratan Sircar 医院(NRS))和私立(阿波罗格伦内尔格医院(AGH))医院以及英国考文垂市全民医保体系下的一家医院(考文垂大学医院及沃里克郡大学医院(UHCW))的 AHF 患者。数据变量改编自英国国家 HF 审计计划,收集时间为 24 个月。对每个中心的院内死亡率和住院时间的预测因素进行了评估。

结果

在 1652 名患者中,政府资助的 NRS 患者的院内死亡率最高(11.9%),而向北 3 英里的 AGH 死亡率明显较低(7.5%,p=0.034),与 UHCW 相似(8%)。这可能归因于不同的 HF 表型以及临床和组织护理方面的差异。如预期的那样,在接受 UHCW 和 NRS 服务的公共医院患者中,低血压与死亡风险显著增加相关。

结论

在一个地区内,以及在私人、公共和全民医保体系下的中低收入与高收入国家之间,HF 的特征、管理和结局存在显著差异。当制定策略解决 HF 领域的本地证据与实践差距时,医生和政策制定者在将国家层面的数据应用于本地时应谨慎行事。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d4f/9157346/2e7fed2d9d65/openhrt-2022-001964f01.jpg

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