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再探莫氏显微外科手术:一种多学科协作方法用于治疗头颈部侵袭性和复发性基底细胞癌

Mohs micrographic surgery revisited: A multidisciplinary, collaborative approach for the treatment of aggressive and recurrent basal cell carcinoma on the head and neck.

作者信息

Aristokleous Iliana, Schultz Inkeri, Vassilaki Ismini, Krynitz Britta, Lapins Jan, Girnita Ada, Nilsson Margareta Frohm

机构信息

Plastic and Reconstructive Surgery, Karolinska University Hospital, 17164, Solna, Stockholm, Sweden.

Plastic and Reconstructive Surgery, Karolinska University Hospital, 17164, Solna, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

出版信息

J Plast Reconstr Aesthet Surg. 2022 Sep;75(9):3373-3383. doi: 10.1016/j.bjps.2022.04.037. Epub 2022 Apr 25.

Abstract

Mohs micrographic surgery is the preferred surgical option for high-risk basal cell carcinomas. In our institution, the method is exclusively used for the treatment of aggressive and recurrent facial tumours selected via multidisciplinary team meetings and consistently managed using a multidisciplinary approach. The aim of this retrospective patient-record study was to examine the outcomes for basal cell carcinomas managed with Mohs micrographic surgery and to present our experience from multidisciplinary team meetings and interdisciplinary collaborations. All patients treated between September 2009 and March 2019 at Karolinska University hospital were included. In a total of 143 facial basal cell carcinomas in 138 patients, 86 primary and 57 recurrent, the recurrence rate was 4.9% after a median follow-up of 24 months. In regions, where highly specialised Mohs surgeons performing all the steps of the procedure are limited, interdisciplinary collaboration can be an effective strategy for appropriate patient selection and for performing all steps of Mohs surgery with dermatosurgeons eradicating the tumour, pathologists evaluating the histopathology, followed by reconstructive surgery by plastic surgeons. The approach we present here provides a robust and functioning Mohs surgical service during the build-up of the organisation, while providing the opportunity to train new surgeons. Once the clinic has been set up, the multidisciplinary approach should always be considered and applied when dealing with complex cases.

摘要

莫氏显微外科手术是高危基底细胞癌的首选手术方式。在我们机构,该方法专门用于治疗通过多学科团队会议筛选出的侵袭性和复发性面部肿瘤,并始终采用多学科方法进行管理。这项回顾性患者记录研究的目的是检查采用莫氏显微外科手术治疗基底细胞癌的结果,并介绍我们在多学科团队会议和跨学科合作方面的经验。纳入了2009年9月至2019年3月在卡罗林斯卡大学医院接受治疗的所有患者。138例患者共143例面部基底细胞癌,其中原发性86例,复发性57例,中位随访24个月后复发率为4.9%。在执行该手术所有步骤的高度专业化莫氏外科医生有限的地区,跨学科合作可能是一种有效的策略,可用于适当选择患者,并由皮肤外科医生切除肿瘤、病理学家评估组织病理学,随后由整形外科医生进行重建手术,从而完成莫氏手术的所有步骤。我们在此介绍的方法在机构建设期间提供了强大且有效的莫氏外科服务,同时提供了培训新外科医生的机会。一旦诊所设立,在处理复杂病例时应始终考虑并应用多学科方法。

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