Goswami Mridula, Baveja C P, Bhushan Urvashi, Sharma Sadhna
Department of Pedodontics and Preventive Dentistry, Maulana Azad Institute of Dental Sciences, New Delhi, India.
Department of Microbiology, Maulana Azad Medical College, New Delhi, India.
Int J Clin Pediatr Dent. 2022;15(Suppl 1):S12-S17. doi: 10.5005/jp-journals-10005-1898.
To compare the efficacy of triple antibiotic paste (TAP) and double antibiotic paste (DAP) for root canal disinfection during revascularization of immature pulpless teeth.
A sample of 20 immature teeth in subjects aged 8-13 years was selected for a revascularization procedure. The teeth were randomly distributed in two groups corresponding to the medicament received-TAP group ( = 10) and DAP group ( = 10). Microbial samples were collected using dry paper points at the beginning of treatment and thereafter every 3 weeks till sterile reading was obtained. Microbial samples were then sent to the microbiological lab for identification.
A variety of opportunistic microbes were detected in samples obtained before placement of medicaments with no significant difference between the two medicament groups. The efficacy of TAP to eliminate microbes was lower in comparison to DAP after 3 weeks of placement of medicaments, whereas it was found to be more efficacious in comparison to DAP after 6 weeks and no significant difference (> 0.05) was observed between the two groups.
Immature permanent teeth with pulp necrosis can achieve complete root development with regenerative endodontic technique. The use of antibiotic pastes including TAP and DAP can help achieve a successful outcome with thorough decontamination of the root canal.
Goswami M, Baveja CP, Bhushan U, Comparative Evaluation of Two Antibiotic Pastes for Root Canal Disinfection. Int J Clin Pediatr Dent 2022;15(S-1):S12-S17.
比较三联抗生素糊剂（TAP）和双联抗生素糊剂（DAP）在年轻恒牙牙髓血管再生治疗中进行根管消毒的效果。
选取8 - 13岁受试者的20颗年轻恒牙进行牙髓血管再生治疗。将牙齿随机分为两组，分别对应使用的药物——TAP组（n = 10）和DAP组（n = 10）。在治疗开始时用干燥纸尖采集微生物样本，此后每3周采集一次，直至获得无菌读数。然后将微生物样本送至微生物实验室进行鉴定。
在放置药物前采集的样本中检测到多种机会性微生物，两组药物之间无显著差异。放置药物3周后，TAP消除微生物的效果低于DAP，而放置6周后，TAP的效果优于DAP，两组之间无显著差异（P>0.05）。
牙髓坏死的年轻恒牙可通过牙髓再生技术实现牙根的完全发育。使用包括TAP和DAP在内的抗生素糊剂有助于通过彻底的根管消毒获得成功的治疗效果。
Goswami M, Baveja CP, Bhushan U, 两种抗生素糊剂用于根管消毒的比较评价。《国际临床儿科牙科学杂志》2022；15（S - 1）：S12 - S17。
