Konde Sapna, Ravindran Shruthi, Agarwal Manisha, Peethambar Preetha
Department of Pedodontics, AECS Maaruthi College of Dental Sciences and Research Center, Bengaluru, Karnataka, India.
Int J Clin Pediatr Dent. 2022;15(Suppl 2):S234-S238. doi: 10.5005/jp-journals-10005-2165.
Prevention of dental caries is paramount in reducing the global burden of the disease. The consumption of probiotics as a prophylactic and therapeutic agent for dental caries, has certain limitations. Prebiotics are nondigestible food ingredients, that enhance the growth and activity of probiotic microorganism, thereby help in the establishment of a healthy oral environment.
The aim of this study was to evaluate and compare the effect of prebiotics, probiotics, and synbiotics on the salivary counts and salivary IgA concentrations.
Children of age-group 6-9 years with DMFT score of 5 and above were divided into three groups of 10 each: Group 1 (prebiotics), Group 2 (probiotics), and Group 3 (synbiotics). The functional food therapy was done for a period of 1 month twice daily. The count and IgA concentrations were assessed pre- and postintervention. The obtained results were subjected to statistical analysis.
A statistically significant reduction of was seen in all three groups after 1 month. However, no statistically significant difference was noted between the groups.
Prebitoics can serve as an unfortified and natural means of combating dental caries.
Konde S, Ravindran S, Agarwal M, Prebiotics-A Primeval Measure to Combat Dental Caries: A Short-term Clinical Study. Int J Clin Pediatr Dent 2022;15(S-2):S234-S238.
预防龋齿对于减轻该疾病的全球负担至关重要。将益生菌作为龋齿的预防和治疗剂使用存在一定局限性。益生元是不可消化的食物成分，可增强益生菌微生物的生长和活性，从而有助于建立健康的口腔环境。
本研究旨在评估和比较益生元、益生菌和合生元对唾液细菌计数和唾液免疫球蛋白A浓度的影响。
将龋失补指数（DMFT）得分5及以上的6至9岁儿童分为三组，每组10人：第1组（益生元组）、第2组（益生菌组）和第3组（合生元组）。进行为期1个月的功能性食品治疗，每天两次。在干预前后评估细菌计数和免疫球蛋白A浓度。对获得的结果进行统计分析。
1个月后，所有三组的细菌计数均有统计学意义的下降。然而，各组之间未观察到统计学意义上的显著差异。
益生元可作为一种未强化的天然抗龋手段。
孔德S，拉温德兰S，阿加瓦尔M，《益生元——对抗龋齿的原始措施：一项短期临床研究》。《国际临床儿科牙科学杂志》2022年；15（S-2）：S234 - S238。
