Anatone Alex J, Richardson Shawn S, Kahlenberg Cynthia A, Gausden Elizabeth B, Figgie Mark P, Blevins Jason L
Hospital for Special Surgery, New York, NY, USA.
HSS J. 2022 May;18(2):290-296. doi: 10.1177/15563316211007812. Epub 2021 Apr 14.
: Younger patients are undergoing total knee arthroplasty (TKA) at increasing rates and may face multiple revisions during their lifetimes due to mechanical complications or infections. : We sought to compare the early complication rates and revision-free implant-survival rates across age groups of patients undergoing TKA, with particular focus on implant survival in younger patients. : We conducted a retrospective analysis of data taken from a national insurance database on patients who underwent primary TKA from 2007 to 2015. Kaplan-Meier curve survival analysis and log rank test were performed to evaluate revision rates in 7 age groups (younger than 40, 40-49, 50-59, 60-69, 70-79, 80-89, and 90 or more years of age). Complication rates were compared to rates in the age 60 to 79 years age groups using multiple logistic regression, controlling for baseline demographics and comorbidities. : There were 114,698 patients included in the analysis. Patients in the younger than 40 years, 40 to 49 years, and 50 to 59 years age groups had increased rates of early mechanical complications; 90-day readmission rates were significantly higher in those age groups as well. Revision-free implant survival at 5 years was significantly worse in patients younger than 60 years of age, particularly those less than 40 years, who had a 77% revision-free implant-survival rate at 5 years. : Younger patients had a higher risk of early revision after TKA, as well as an increased rate of mechanical complications and readmissions at 90 days. These outcomes suggest more study is needed to better understand these discrepancies and to better guide preoperative counseling for young patients considering TKA.
年轻患者接受全膝关节置换术(TKA)的比例在不断上升,并且由于机械并发症或感染,他们在一生中可能面临多次翻修手术。我们试图比较接受TKA的不同年龄组患者的早期并发症发生率和无翻修植入物生存率,特别关注年轻患者的植入物生存率。我们对2007年至2015年接受初次TKA的患者的国家保险数据库数据进行了回顾性分析。采用Kaplan-Meier曲线生存分析和对数秩检验来评估7个年龄组(小于40岁、40-49岁、50-59岁、60-69岁、70-79岁、80-89岁和90岁及以上)的翻修率。使用多因素逻辑回归比较并发症发生率与60至79岁年龄组的发生率,并对基线人口统计学和合并症进行控制。分析纳入了114,698名患者。年龄小于40岁、40至49岁和50至59岁组的患者早期机械并发症发生率增加;这些年龄组的90天再入院率也显著更高。60岁以下患者5年无翻修植入物生存率显著更差,尤其是小于40岁的患者,其5年无翻修植入物生存率为77%。年轻患者TKA后早期翻修风险更高,以及90天时机械并发症和再入院率增加。这些结果表明,需要更多研究来更好地理解这些差异,并更好地指导考虑TKA的年轻患者的术前咨询。