• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[妊娠与分娩对氨苄西林药代动力学影响的临床研究]

[Clinical studies on the effect of pregnancy and labor on the pharmacokinetics of ampicillin].

作者信息

Voigt R, Schröder S, Meinhold P, Zenner I, Nöschel H

出版信息

Zentralbl Gynakol. 1978;100(11):701-5.

PMID:356490
Abstract

After giving 5 g Ampicillin intravenously to a total of 33 women (gravidae during the VIII. month pregnancy, women in labor and health controll persons) the serum levels of the mothers were analysed according to the pharmacokinetic parameter half-life of elimination.--Our results show that only the delivery cause significant differences of the kinetic of ampicillin.--Our results are discussed with the data given by literature.

摘要

对总共33名女性(妊娠第八个月的孕妇、分娩期女性和健康对照者)静脉注射5克氨苄西林后,根据消除半衰期这一药代动力学参数分析了母亲们的血清水平。——我们的结果表明,只有分娩会导致氨苄西林动力学的显著差异。——我们将根据文献给出的数据对我们的结果进行讨论。

相似文献

1
[Clinical studies on the effect of pregnancy and labor on the pharmacokinetics of ampicillin].[妊娠与分娩对氨苄西林药代动力学影响的临床研究]
Zentralbl Gynakol. 1978;100(11):701-5.
2
[The pharmacokinetics of ampicillin in pregnant women with H-gestosis in the last trimester of pregnancy].[妊娠晚期患妊娠高血压综合征孕妇氨苄西林的药代动力学]
Pharmazie. 1985 Jul;40(7):480-1.
3
[Pharmacokinetics of antibiotics and sulfanilamides in pregnancy and labor].[孕期及分娩期抗生素与磺胺类药物的药代动力学]
Zentralbl Gynakol. 1982;104(23):1514-8.
4
The absorption of ampicillin in late pregnancy and labour.氨苄西林在妊娠晚期及分娩时的吸收情况。
N Z Med J. 1974 Dec 11;80(529):500-1.
5
Pharmacokinetics during pregnancy and delivery.
Int J Biol Res Pregnancy. 1982;3(2):66-8.
6
[Pharmacokinetics of cefotaxime during late pregnancy].[头孢噻肟在妊娠晚期的药代动力学]
Z Geburtshilfe Perinatol. 1989 Sep-Oct;193(5):230-2.
7
[The pharmacokinetics of azlocillin after single and multiple intravenous injections during the third trimester].[孕晚期单次及多次静脉注射阿洛西林后的药代动力学]
Zentralbl Gynakol. 1988;110(15):944-8.
8
[Pharmacokinetic investigations of the transfer of antibiotics into amniotic fluid. Part III: Oxacillin (author's transl)].抗生素向羊水转移的药代动力学研究。第三部分:苯唑西林(作者译)
Z Geburtshilfe Perinatol. 1975 Oct;179(5):346-55.
9
Pharmacokinetics of potassium ampicillin.氨苄西林钾的药代动力学
Arzneimittelforschung. 1980;30(6):1019-21.
10
[Ampicillin pharmacokinetics in pregnant women with acute pyelonephritis].[氨苄西林在急性肾盂肾炎孕妇中的药代动力学]
Antibiot Med Biotekhnol. 1985 Mar;30(3):228-32.

引用本文的文献

1
Pregnancy-Associated Changes in Pharmacokinetics: A Systematic Review.妊娠相关的药代动力学变化:一项系统评价。
PLoS Med. 2016 Nov 1;13(11):e1002160. doi: 10.1371/journal.pmed.1002160. eCollection 2016 Nov.
2
The influence of labour on the pharmacokinetics of intravenously administered amoxicillin in pregnant women.分娩对孕妇静脉注射阿莫西林药代动力学的影响。
Br J Clin Pharmacol. 2008 Dec;66(6):866-74. doi: 10.1111/j.1365-2125.2008.03292.x.
3
Pharmacokinetic changes during pregnancy and their clinical relevance.孕期的药代动力学变化及其临床意义。
Clin Pharmacokinet. 1997 Nov;33(5):328-43. doi: 10.2165/00003088-199733050-00002.
4
Review of beta-lactam antibiotics in pregnancy. The need for adjustment of dosage schedules.孕期β-内酰胺类抗生素综述。调整给药方案的必要性。
Clin Pharmacokinet. 1994 Jul;27(1):49-62. doi: 10.2165/00003088-199427010-00005.
5
Pharmacokinetics of antibiotics in pregnancy and labour.抗生素在妊娠及分娩期的药代动力学
Clin Pharmacokinet. 1979 Jul-Aug;4(4):297-309. doi: 10.2165/00003088-197904040-00003.