Trottier Kathryn, Monson Candice M, Kaysen Debra, Wagner Anne C, Liebman Rachel E, Abbey Susan E
University Health Network, Toronto, ON, Canada.
Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Transl Psychiatry. 2022 Jun 1;12(1):222. doi: 10.1038/s41398-022-01965-3.
Many healthcare workers on the frontlines of the COVID-19 pandemic are experiencing clinical levels of mental health symptoms. Evidence-based interventions to address these symptoms are urgently needed. RESTORE (Recovering from Extreme Stressors Through Online Resources and E-health) is an online guided transdiagnostic intervention including cognitive-behavioral interventions. It was specifically designed to improve symptoms of anxiety, depression, and posttraumatic stress disorder (PTSD) associated with COVID-19-related traumatic and extreme stressors. The aims of the present study were to assess the feasibility, acceptability, and initial efficacy of RESTORE in healthcare workers on the frontline of the COVID-19 pandemic. We conducted an initial uncontrolled trial of RESTORE in 21 healthcare workers who were exposed to COVID-19-related traumatic or extremely stressful experiences in the context of their work and who screened positive for clinical levels of anxiety, depression, and/or PTSD symptoms. RESTORE was found to be feasible and safe, and led to statistically significant and large effect size improvements in anxiety, depression, and PTSD symptoms over the course of the intervention through follow-up. RESTORE has the potential to become a widely disseminable evidence-based intervention to address mental health symptoms associated with mass traumas.Clinical Trials Registration: This trial was registered with ClinicalTrials.gov ID: NCT04873622.
许多奋战在新冠疫情一线的医护人员正经历着临床水平的心理健康症状。迫切需要基于证据的干预措施来解决这些症状。RESTORE（通过在线资源和电子健康从极端压力源中恢复）是一种在线引导式跨诊断干预措施，包括认知行为干预。它专门设计用于改善与新冠疫情相关的创伤性和极端压力源所导致的焦虑、抑郁和创伤后应激障碍（PTSD）症状。本研究的目的是评估RESTORE在新冠疫情一线医护人员中的可行性、可接受性和初步疗效。我们对21名医护人员进行了RESTORE的初始非对照试验，这些医护人员在工作中接触到了与新冠疫情相关的创伤性或极具压力的经历，并且焦虑、抑郁和/或PTSD症状的临床水平筛查呈阳性。结果发现，RESTORE是可行且安全的，并且在干预过程直至随访期间，焦虑、抑郁和PTSD症状均有统计学上显著且效果显著的改善。RESTORE有潜力成为一种可广泛传播的基于证据的干预措施，以解决与大规模创伤相关的心理健康症状。临床试验注册：本试验已在ClinicalTrials.gov注册，ID：NCT04873622。
