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复杂网络中的相对、局部和全局维度。

Relative, local and global dimension in complex networks.

机构信息

Department of Mathematics, Imperial College, London, SW7 2AZ, UK.

Department of Neurology, University Hospital Würzburg, Würzburg, Germany.

出版信息

Nat Commun. 2022 Jun 2;13(1):3088. doi: 10.1038/s41467-022-30705-w.

Abstract

Dimension is a fundamental property of objects and the space in which they are embedded. Yet ideal notions of dimension, as in Euclidean spaces, do not always translate to physical spaces, which can be constrained by boundaries and distorted by inhomogeneities, or to intrinsically discrete systems such as networks. To take into account locality, finiteness and discreteness, dynamical processes can be used to probe the space geometry and define its dimension. Here we show that each point in space can be assigned a relative dimension with respect to the source of a diffusive process, a concept that provides a scale-dependent definition for local and global dimension also applicable to networks. To showcase its application to physical systems, we demonstrate that the local dimension of structural protein graphs correlates with structural flexibility, and the relative dimension with respect to the active site uncovers regions involved in allosteric communication. In simple models of epidemics on networks, the relative dimension is predictive of the spreading capability of nodes, and identifies scales at which the graph structure is predictive of infectivity. We further apply our dimension measures to neuronal networks, economic trade, social networks, ocean flows, and to the comparison of random graphs.

摘要

维度是物体及其所处空间的基本属性。然而,理想的维度概念,如欧几里得空间,并不总是适用于物理空间,物理空间可能受到边界的限制和不均匀性的扭曲,或者适用于内在离散的系统,如网络。为了考虑局部性、有限性和离散性,可以使用动力过程来探测空间几何形状并定义其维度。在这里,我们表明,对于扩散过程的源,空间中的每个点都可以分配一个相对维度,这一概念为局部和全局维度提供了一个依赖于尺度的定义,也适用于网络。为了展示其在物理系统中的应用,我们证明了结构蛋白图的局部维度与结构灵活性相关,而相对于活性部位的相对维度则揭示了参与变构通讯的区域。在网络上传染病的简单模型中,相对维度可以预测节点的传播能力,并确定图结构可预测传染性的尺度。我们进一步将我们的维度度量应用于神经元网络、经济贸易、社交网络、海洋流动以及随机图的比较。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b79/9163155/55cb7e918a95/41467_2022_30705_Fig1_HTML.jpg

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