School of Nursing and Rehabilitation, Shandong University, Jinan, 250012, Shandong, China.
J Cardiothorac Surg. 2022 Jun 3;17(1):139. doi: 10.1186/s13019-022-01824-8.
To compare the influence of minimally invasive esophagectomy (MIE) and open esophagectomy (OE) on postoperative pulmonary function in patients with esophageal cancer.
Studies about the influence of MIE and OE on postoperative pulmonary function in esophageal cancer patients were searched from PubMed, EMBASE, the Cochrane Library, CNKI, Chinese Science and Technology Journal Database, CBM, and Wanfang Data from inception to March 18, 2021. Meta-analysis was performed using the RevMan 5.3.
This analysis included eight studies, enrolling 264 patients who underwent MIE and 257 patients who underwent OE. The meta-analysis results showed that the MIE group had a higher outcome regarding the percent predicted vital capacity (%VC), forced vital capacity (FVC), forced expiratory volume in 1 s (FEV), and maximum voluntary ventilation (MVV) 1 month after surgery than the OE group. In addition, those who underwent MIE had lower ΔVC%, ΔFVC, and ΔFEV between pre-operation and 1 month after surgery than those who underwent OE. There is no statistical difference between the two groups in ΔMVV.
Compared with OE, MIE has a more protective effect on postoperative pulmonary function. However, due to the small number of included literature and all cohort studies, this finding needs to be validated with larger samples and higher quality RCT studies.
比较微创食管切除术（MIE）和开放食管切除术（OE）对食管癌患者术后肺功能的影响。
从 PubMed、EMBASE、Cochrane 图书馆、中国知网、中国科技期刊数据库、CBM 和万方数据中检索了从建库到 2021 年 3 月 18 日有关 MIE 和 OE 对食管癌患者术后肺功能影响的研究。使用 RevMan 5.3 进行 Meta 分析。
本分析纳入了 8 项研究，共纳入 264 例接受 MIE 和 257 例接受 OE 的患者。Meta 分析结果显示，MIE 组术后 1 个月时预测肺活量百分比（%VC）、用力肺活量（FVC）、1 秒用力呼气容积（FEV）和最大自主通气量（MVV）的结果更高。此外，与 OE 组相比，MIE 组患者术后 1 个月时的 VC%、FVC%和 FEV%下降幅度更小。两组间 MVV 的ΔMVV 无统计学差异。
与 OE 相比，MIE 对术后肺功能具有更好的保护作用。然而，由于纳入文献数量较少且均为队列研究，该结论需要更大样本量和更高质量的 RCT 研究来验证。
