Miyata Kazushi, Fukaya Masahide, Itatsu Keita, Abe Tetsuya, Nagino Masato
Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan.
Surg Today. 2016 Jul;46(7):807-14. doi: 10.1007/s00595-015-1240-1. Epub 2015 Aug 27.
The aim of this study was to investigate whether muscle sparing thoracotomy (MST) improved postoperative chest pain and an impairment of the postoperative pulmonary function in comparison with posterolateral thoracotomy (PLT).
Twenty-four patients with esophageal cancer who underwent PLT from September 2006 to August 2008 and 30 patients who underwent MST from September 2008 to August 2010 were selected as subjects of this study. Postoperative acute and chronic chest pain and the recovery of the pulmonary function were retrospectively compared between the two groups.
The frequency of the additional use of analgesics was on days 3, 6, and 7 (mean 0.4 vs. 1.2, p = 0.027, 0.4 vs. 1.5, p = 0.007, and 0.2 vs. 1.2, p = 0.009, respectively) in the early postoperative period. The number of patients requiring analgesics at 1 and 3 months after surgery was significantly lower in the MST group than in the PLT group (13.3 vs. 58.3 %, p = 0.002, 10.0 vs. 50.0 %, p = 0.001, respectively). The postoperative vital capacity, expressed as a percentage of the preoperative value, 3 and 12 months after surgery was significantly higher in the MST group than in the PLT group (86.0 vs. 73.8 %, p = 0.028, 93.2 vs. 76.9 %, p = 0.002, respectively).
Compared with PLT, MST might, therefore, reduce postoperative chest pain and offer a better recovery of pulmonary function in patients with esophageal cancer.
本研究旨在探讨与后外侧开胸术(PLT)相比,保留肌肉开胸术(MST)是否能改善术后胸痛及术后肺功能损害。
选取2006年9月至2008年8月接受PLT的24例食管癌患者以及2008年9月至2010年8月接受MST的30例患者作为本研究对象。回顾性比较两组患者术后急性和慢性胸痛情况以及肺功能恢复情况。
术后早期,在第3、6和7天,额外使用镇痛药的频率分别为(平均0.4比1.2,p = 0.027;0.4比1.5,p = 0.007;0.2比1.2,p = 0.009)。MST组术后1个月和3个月需要镇痛药的患者数量显著低于PLT组(分别为13.3%比58.3%,p = 0.002;10.0%比50.0%,p = 0.001)。术后3个月和12个月,以术前值的百分比表示的肺活量,MST组显著高于PLT组(分别为86.0%比73.8%,p = 0.028;93.2%比76.9%,p = 0.002)。
因此,与PLT相比,MST可能减轻食管癌患者的术后胸痛,并使肺功能得到更好的恢复。