Department of Periodontology, Adhiparasakthi Dental College and Hospital, Melmaruvathur, Tamil Nadu, India, Phone: +91 8754632742, e-mail:
Department of Periodontology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India.
J Contemp Dent Pract. 2021 Dec 1;22(12):1413-1416.
The main aim of the study was to evaluate the systemic markers related to anemia in generalized aggressive periodontitis (GAgP) patients before and after phase I therapy.
Based on the inclusion criteria, 15 patients with GAgP were allocated to two groups, group A (before phase I periodontal therapy) and group B (after phase I periodontal therapy). After 3 months, clinical parameters and hematological parameters were reevaluated.
The hematological parameters like hemoglobin (Hb) and red blood cell (RBC) counts were increased significantly after therapy in group B with a significant improvement in the plaque index score, gingival bleeding index score with a reduction of probing depth, and a gain in clinical attachment levels.
Within the limitation of this study, it could be concluded that GAgP was associated with reduced RBC parameters suggesting that it may tend toward anemia of chronic disease (ACD). Nonsurgical periodontal therapy (NSPT) not only reverses the periodontal health by reducing the inflammation but also improves the anemic status.
Based on several studies, it was concluded that chronic periodontitis is associated with ACD. This study results indicate that like chronic periodontitis, aggressive periodontitis is also associated with reduced RBC and Hb count suggesting the risk for ACD. So when a patient is diagnosed to have any chronic infectious disease that might lead to ACD, then it is mandatory to treat that particular disease in order to reduce the infection so as to reverse the anemic status of an individual.
本研究的主要目的是评估广泛性侵袭性牙周炎（GAgP）患者在 I 期治疗前后与贫血相关的系统标志物。
根据纳入标准，将 15 名 GAgP 患者分配到两组，A 组（I 期牙周治疗前）和 B 组（I 期牙周治疗后）。3 个月后，重新评估临床参数和血液学参数。
B 组治疗后血液学参数如血红蛋白（Hb）和红细胞（RBC）计数显著增加，斑块指数评分、牙龈出血指数评分显著改善，探诊深度减少，临床附着水平增加。
在本研究的限制范围内，可以得出结论，GAgP 与 RBC 参数减少有关，提示其可能倾向于慢性病贫血（ACD）。非手术性牙周治疗（NSPT）不仅通过减少炎症来逆转牙周健康，还改善贫血状况。
根据多项研究，慢性牙周炎与 ACD 有关。本研究结果表明，与慢性牙周炎一样，侵袭性牙周炎也与 RBC 和 Hb 计数减少有关，提示存在 ACD 的风险。因此，当患者被诊断患有任何可能导致 ACD 的慢性传染病时，必须治疗该特定疾病，以减少感染，从而逆转个体的贫血状况。
