Knudson R J, Kaltenborn W T, Knudson D E, Burrows B
Am Rev Respir Dis. 1987 Apr;135(4):805-11. doi: 10.1164/arrd.1987.135.4.805.
Measurements of the single-breath carbon monoxide diffusing capacity (DL) were obtained on a randomly selected sample representative of the white non-Mexican-American population of Tucson, Arizona. Methods of measurement followed the guidelines set forth in the ATS-sponsored Epidemiology Standardization Project. There were 228 healthy nonsmokers who had duplicate tests that met the criteria for being acceptable. On the basis of data from these subjects, reference equations were derived for DL, alveolar volume (VA), and DL/VA. The data demonstrate the effects of growth and development, height, and age on these variables. Because a significant proportion of women, but not of men, had low hematocrit values, an effect of hematocrit on DL and DL/VA could be demonstrated only in females in this population sample.
对亚利桑那州图森市非墨西哥裔美国白人人群中随机抽取的一个代表性样本进行了单次呼吸一氧化碳弥散量（DL）的测量。测量方法遵循美国胸科学会（ATS）发起的流行病学标准化项目所规定的指南。有228名健康非吸烟者进行了重复测试，且测试结果符合可接受标准。基于这些受试者的数据，推导出了DL、肺泡容积（VA）和DL/VA的参考方程。数据显示了生长发育、身高和年龄对这些变量的影响。由于该人群样本中相当一部分女性（而非男性）的血细胞比容值较低，因此仅在女性中证明了血细胞比容对DL和DL/VA的影响。
