ICMR-National Institute for Research in Environmental Health, Bhopal Bypass Road, Bhouri, Bhopal, Madhya Pradesh, 462030, India.
Department of Hematology, Stem Cell Research Centre, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, 226014, India.
Sci Rep. 2022 Jun 3;12(1):9252. doi: 10.1038/s41598-022-13489-3.
Contamination of drinking water with endocrine-disrupting chemicals (EDCs) raises concerns over the security and long-term sustainability of clean water supplies as well as human exposure via daily water intake. In this study, the seasonal disparity and occurrence of six phthalates and bisphenol-A in the drinking water supply system and associated health-risk were examined. The detection frequencies of the ∑6PAEs ranged from 24 to 100% in the winter whereas; in summer it is below the detection limit up to 100%. DEHP was the most prevalent phthalate congener ranging from 1.14 to 8351.85 µg/L (winter) and 0.552 to 410.29 µg/L (summer) surpassing the permissible limit. However, BPA concentrations were found under the permissible limit. The results suggested that PAEs concentration displayed significant seasonal variations with the highest in winter and the lowest in summer. The exposure to PAEs and BPA from drinking water was assessed, indicating a possible health risk to humans with a hazard quotient (HQ) > 1 for DEHP only. The findings necessitate an immediate scrutiny of these EDCs in drinking water supply system and are critical for implementing effective technologies at the WTP scale to ensure the quality and safety of drinking water to ascertain human and environmental health.
饮用水中内分泌干扰化学物质(EDCs)的污染引发了人们对清洁饮用水供应安全性和长期可持续性的担忧,以及人类通过日常饮水暴露于这些物质的风险。在本研究中,我们检测了饮用水供应系统中六种邻苯二甲酸酯和双酚 A 的季节性差异和出现情况,以及相关的健康风险。在冬季,∑6PAEs 的检测频率在 24%到 100%之间,而在夏季,其检测频率高达 100%。在冬季,DEHP 是最常见的邻苯二甲酸酯同系物,浓度范围为 1.14 到 8351.85μg/L,而在夏季,浓度范围为 0.552 到 410.29μg/L,均超过了允许的浓度范围。然而,BPA 的浓度低于允许的浓度范围。结果表明,PAEs 浓度呈现出显著的季节性变化,冬季浓度最高,夏季浓度最低。通过评估饮用水中 PAEs 和 BPA 的暴露情况,发现仅 DEHP 的危害系数(HQ)>1,可能对人体健康造成风险。这些发现需要立即对饮用水供应系统中的这些 EDCs 进行审查,对于在 WTP 规模上实施有效的技术以确保饮用水的质量和安全,从而确保人类和环境健康至关重要。