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Suppression by Saccharomyces boulardii of toxigenic Clostridium difficile overgrowth after vancomycin treatment in hamsters.布拉氏酵母菌对万古霉素治疗后仓鼠中产毒艰难梭菌过度生长的抑制作用
Antimicrob Agents Chemother. 1987 Jan;31(1):129-31. doi: 10.1128/AAC.31.1.129.
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[Comparative effect of a single or continuous administration of "Saccharomyces boulardii" on the establishment of various strains of "candida" in the digestive tract of gnotobiotic mice].[单剂量或连续给药“布拉酵母菌”对悉生小鼠消化道中各种念珠菌菌株定植的比较效果]
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布拉氏酵母菌对万古霉素治疗后仓鼠中产毒艰难梭菌过度生长的抑制作用

Suppression by Saccharomyces boulardii of toxigenic Clostridium difficile overgrowth after vancomycin treatment in hamsters.

作者信息

Elmer G W, McFarland L V

出版信息

Antimicrob Agents Chemother. 1987 Jan;31(1):129-31. doi: 10.1128/AAC.31.1.129.

DOI:10.1128/AAC.31.1.129
PMID:3566236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC174670/
Abstract

Saccharomyces boulardii prevented the development of high counts of Clostridium difficile, high titers of toxin B, and positive latex agglutination tests after cessation of vancomycin treatment for hamsters. The protocol used was designed to stimulate relapse of human C. difficile-associated colitis. S. boulardii was protective in this model.

摘要

布拉氏酵母菌可预防仓鼠万古霉素治疗停止后艰难梭菌高计数、高滴度毒素B以及乳胶凝集试验阳性的情况出现。所采用的方案旨在刺激人类艰难梭菌相关性结肠炎的复发。在该模型中，布拉氏酵母菌具有保护作用。