布拉氏酵母菌对万古霉素治疗后仓鼠中产毒艰难梭菌过度生长的抑制作用
Suppression by Saccharomyces boulardii of toxigenic Clostridium difficile overgrowth after vancomycin treatment in hamsters.
作者信息
Elmer G W, McFarland L V
出版信息
Antimicrob Agents Chemother. 1987 Jan;31(1):129-31. doi: 10.1128/AAC.31.1.129.
Abstract
Saccharomyces boulardii prevented the development of high counts of Clostridium difficile, high titers of toxin B, and positive latex agglutination tests after cessation of vancomycin treatment for hamsters. The protocol used was designed to stimulate relapse of human C. difficile-associated colitis. S. boulardii was protective in this model.
摘要
布拉氏酵母菌可预防仓鼠万古霉素治疗停止后艰难梭菌高计数、高滴度毒素B以及乳胶凝集试验阳性的情况出现。所采用的方案旨在刺激人类艰难梭菌相关性结肠炎的复发。在该模型中，布拉氏酵母菌具有保护作用。
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