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酒精性肝病及酒精摄入对性激素水平的影响。

The effects of alcoholic liver disease and alcohol ingestion on sex hormone levels.

作者信息

Gordon G G, Southren A L, Lieber C S

出版信息

Alcohol Clin Exp Res. 1978 Jul;2(3):259-63. doi: 10.1111/j.1530-0277.1978.tb05809.x.

DOI:10.1111/j.1530-0277.1978.tb05809.x
PMID:356647
Abstract

This study showed that alcohol significantly decreases plasma testosterone levels, with changes noted as early as the first day of alcohol use (loss of pulsatile secretion). This effect is due, in part, to a direct testicular action since it occurred without LH suppression and in the presence of elevated LH levels. More chronic use of alcohol resulted in a suppression of LH. Thus, alcohol use in nonalcoholic men is associated with an effect both at the testicular and hypothalamic-pituitary levels.

摘要

这项研究表明,酒精会显著降低血浆睾酮水平,早在饮酒第一天就可观察到变化(脉冲式分泌丧失)。这种效应部分归因于对睾丸的直接作用,因为它在未抑制促黄体生成素(LH)且LH水平升高的情况下发生。长期饮酒会导致LH受到抑制。因此,非酒精性男性饮酒会对睾丸以及下丘脑 - 垂体水平均产生影响。

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