Mills Krystal, Fatima Shaheen, Fas Norberto
Internal Medicine Program, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA.
Case Rep Gastrointest Med. 2022 May 27;2022:5943468. doi: 10.1155/2022/5943468. eCollection 2022.
Crohn's disease and sarcoidosis are characterized by noncaseating granulomas, but rarely do they present in the same patient. Their coexistence presents a diagnostic challenge as they are often classified as clinically separate, despite their similarities. We present a case of a 59-year-old man previously diagnosed with pulmonary sarcoidosis who presented to the emergency room with abdominal pain and diarrhea. Colonoscopy revealed multiple ulcers in the colon, with histology in keeping with newly diagnosed Crohn's colitis. The patient had a good clinical response to initiation of steroid therapy and a tumor necrosis factor (TNF) inhibitor.
克罗恩病和结节病的特征均为非干酪样肉芽肿，但它们很少出现在同一患者身上。尽管二者存在相似之处，但由于它们在临床上通常被分类为不同疾病，因此其共存带来了诊断挑战。我们报告一例59岁男性患者，该患者此前被诊断为肺部结节病，现因腹痛和腹泻就诊于急诊室。结肠镜检查发现结肠有多处溃疡，组织学检查结果符合新诊断的克罗恩结肠炎。该患者在开始使用类固醇疗法和肿瘤坏死因子（TNF）抑制剂后临床反应良好。
