Department of Radiology, Ronald Reagan-UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States.
Department of Radiology, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Br J Radiol. 2022 Aug 1;95(1136):20211165. doi: 10.1259/bjr.20211165. Epub 2022 Jun 22.
We aimed to investigate if the use of read-out segmented echoplanar imaging with additional two-dimensional navigator correction (Readout Segmentation of Long Variable Echo, RESOLVE) for acquiring prostate diffusion-weighted imaging (DWI) improves image quality, compared to single-shot echoplanar imaging (ss-EPI).
This single-center prospective study cohort included 162 males with suspected prostate cancer, who underwent 3 Tesla multiparametric MRI (3T-mpMRI). Two abdominal radiologists, blinded to the clinical information, separately reviewed each 3T-mpMRI study to rank geometrical distortion, degree of rectal distention, lesion conspicuity, and anatomic details delineation first on ss-EPI-DWI and later on RESOLVE-DWI using 5-point scales (1 = excellent, 5 = poor). The average of the ranking scores given by two readers was generated and used as the final score.
There was good-to-excellent interreader agreement for scoring image quality parameters on both ss-EPI and RESOLVE. Geometrical distortion scores > 3 was seen in 12.3% (20/162) of ss-EPI images, with all having geometrical distortion score <3 on RESOLVE ( < .001). The mean image distortion score was significantly less on RESOLVE than ss-EPI (1.16 1.61, < .01 regardless of rectal gas, .05 when stratified by the degree of rectal distention ). RESOLVE was superior to ss-EPI for lesion conspicuity (mean 1.35 1.53, .002) and anatomic delineation (2.60 2.68, .001) of prostate on DWI.
Compared to conventional ss-EPI, the use of RESOLVE for acquisition of prostate DWI resulted in significantly enhanced image quality and reduced geometrical distortion.
RESOLVE could be an alternative or replacement of ss-EPI for acquiring prostate DWI with significantly less geometrical distortion and significantly improved lesion conspicuity and anatomic delineation.
本研究旨在探究在获取前列腺扩散加权成像（DWI）时，使用带二维导航校正的分段读出回波平面成像（Readout Segmentation of Long Variable Echo，RESOLVE）是否能比单次激发回波平面成像（ss-EPI）提高图像质量。
本研究纳入了 162 名疑似前列腺癌的男性患者，所有患者均接受了 3 特斯拉多参数磁共振成像（3T-mpMRI）检查。两名腹部放射科医生在不了解临床信息的情况下，分别对每位患者的 3T-mpMRI 检查结果进行评估，使用 5 分制对几何变形、直肠扩张程度、病灶显示程度和解剖细节勾画的程度进行评分（1=极好，5=极差）。两位观察者的评分平均值作为最终评分。
ss-EPI 和 RESOLVE 上的图像质量参数评分具有良好到极好的观察者间一致性。ss-EPI 图像中 12.3%（20/162）的图像存在>3 分的几何变形，而所有 RESOLVE 图像的几何变形评分均<3（<0.001）。RESOLVE 的图像变形评分显著低于 ss-EPI（均<0.01，无论直肠气体情况如何；<0.05，按直肠扩张程度分层）。与 ss-EPI 相比，RESOLVE 能更清晰地显示病灶（平均评分 1.35 1.53，<0.002），且能更好地勾画前列腺的解剖结构（平均评分 2.60 2.68，<0.001）。
与传统的 ss-EPI 相比，使用 RESOLVE 采集前列腺 DWI 可显著提高图像质量，减少几何变形。
与 ss-EPI 相比，RESOLVE 采集前列腺 DWI 的几何变形更小，病灶显示程度和解剖结构勾画程度明显提高，可作为替代或补充方法。
