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年轻女性长新冠后出现间歇性左束支传导阻滞、间隔闪烁和直立位心动过速综合征。

Intermittent left bundle branch block with septal flash and postural orthostatic tachycardia syndrome in a young woman with long COVID-19.

机构信息

Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.

Emergency Care Clinic, Haukeland University Hospital, Bergen, Norway.

出版信息

BMJ Case Rep. 2022 Jun 7;15(6):e249608. doi: 10.1136/bcr-2022-249608.

DOI:10.1136/bcr-2022-249608
PMID:35672052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9174810/
Abstract

The emerging entity, long COVID -19 is characterised by long-lasting dyspnoea, fatigue, cognitive dysfunction and other symptoms. Cardiac involvement manifested as conduction abnormalities, left ventricle mechanical dyssynchrony, dyspnoea, palpitation and postural orthostatic tachycardia syndrome (POTS) are common in long COVID-19. The direct viral damage to the myocardium or immune-mediated inflammation are postulated mechanisms. A woman in her forties presented with a 2-month history of chest pain, functional dyspnoea, palpitation and an episode of syncope after having been home-isolated for mild COVID infection. During clinical workup, a clustering of ECG and echocardiographic abnormalities including left bundle branch block, septal flash, and presystolic wave on spectral Doppler echocardiography, and POTS were detected. The echocardiographic findings together with POTS and persistent dyspnoea indicated the presence of a long COVID-19 state. The prevalence and clinical significance of these finding, as well as the impact on long-term prognosis, should be investigated in future studies.

摘要

新兴实体,长新冠 -19 的特征是持久的呼吸困难、疲劳、认知功能障碍和其他症状。心脏受累表现为传导异常、左心室机械不同步、呼吸困难、心悸和直立性心动过速综合征(POTS)在长新冠 -19 中很常见。推测其机制是病毒对心肌的直接损伤或免疫介导的炎症。一位四十多岁的女性因在家中隔离轻度 COVID 感染后出现胸痛、呼吸困难、心悸和晕厥发作,已持续 2 个月。在临床检查期间,发现一系列心电图和超声心动图异常,包括左束支传导阻滞、室间隔闪光、频谱多普勒超声心动图收缩前波和 POTS。超声心动图发现以及 POTS 和持续呼吸困难表明存在长新冠 -19 状态。这些发现的患病率和临床意义,以及对长期预后的影响,应在未来的研究中进行调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/7371fc9fbac2/bcr-2022-249608f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/e3efcb0dbe63/bcr-2022-249608f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/a44f114f76d8/bcr-2022-249608f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/ff346b125e64/bcr-2022-249608f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/7371fc9fbac2/bcr-2022-249608f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/e3efcb0dbe63/bcr-2022-249608f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/a44f114f76d8/bcr-2022-249608f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/ff346b125e64/bcr-2022-249608f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c7a/9174810/7371fc9fbac2/bcr-2022-249608f04.jpg

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