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新型冠状病毒肺炎相关直立位心动过速综合征:机制、临床过程和管理的当代综述。

Postural Orthostatic Tachycardia Syndrome in COVID-19: A Contemporary Review of Mechanisms, Clinical Course and Management.

机构信息

Department of Cardiology, Debakey Cardiovascular Institute, Houston Methodist, Houston, TX, USA.

University of California San Diego, La Jolla, CA, USA.

出版信息

Vasc Health Risk Manag. 2023 May 12;19:303-316. doi: 10.2147/VHRM.S380270. eCollection 2023.

DOI:10.2147/VHRM.S380270
PMID:37204997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10187582/
Abstract

The long-term implications of COVID-19 have garnered increasing interest in recent months, with Long-COVID impacting over 65 million individuals worldwide. Postural orthostatic tachycardia syndrome (POTS) has emerged as an important component of the Long-COVID umbrella, estimated to affect between 2 and 14% of survivors. POTS remains very challenging to diagnose and manage - this review aims to provide a brief overview of POTS as a whole and goes on to summarize the available literature pertaining to POTS in the setting of COVID-19. We provide a review of available clinical reports, outline proposed pathophysiological mechanisms and end with a brief note on management considerations.

摘要

近几个月来,人们对 COVID-19 的长期影响越来越感兴趣,全球有超过 6500 万人受到长期 COVID 的影响。体位性心动过速综合征(POTS)已成为长期 COVID 的一个重要组成部分,据估计,有 2%至 14%的幸存者受到影响。POTS 的诊断和管理仍然极具挑战性——这篇综述旨在全面概述 POTS,并总结 COVID-19 背景下关于 POTS 的现有文献。我们回顾了现有的临床报告,阐述了提出的病理生理机制,并简要介绍了管理注意事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b67/10187582/629a2fbd4dfb/VHRM-19-303-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b67/10187582/1cfbedfb4b4f/VHRM-19-303-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b67/10187582/629a2fbd4dfb/VHRM-19-303-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b67/10187582/1cfbedfb4b4f/VHRM-19-303-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b67/10187582/629a2fbd4dfb/VHRM-19-303-g0002.jpg

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Nat Cardiovasc Res. 2022 Dec;1(12):1187-1194. doi: 10.1038/s44161-022-00177-8. Epub 2022 Dec 12.
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Long COVID: major findings, mechanisms and recommendations.长新冠:主要发现、机制和建议。
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Overlapping Myocarditis and Postural Orthostatic Tachycardia Syndrome After COVID-19 Messenger RNA Vaccination: A Case Report.
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Sci Rep. 2024 Aug 28;14(1):20017. doi: 10.1038/s41598-024-71055-5.
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Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID.纤维蛋白样微凝块在体位性直立性心动过速综合征(POTS)中的可能作用:关注长期新冠症状
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