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实验性微动脉移植:冻干异种移植与自体移植

Experimental microarterial grafts: freeze-dried heterografts versus autografts.

作者信息

So Y C, Chow S P

出版信息

Br J Plast Surg. 1987 Mar;40(2):188-92. doi: 10.1016/0007-1226(87)90194-9.

DOI:10.1016/0007-1226(87)90194-9
PMID:3567453
Abstract

Segments of the femoral artery from New Zealand white rabbits were removed and freeze-dried. They wer then used as a graft for a defect in the femoral artery of a Sprague-Dawley rat. The femoral artery on the other side of this recipient rat had a similar grafting procedure using a segment of its own femoral artery, thus acting as a control. The patency rate of the freeze-dried heterografts was comparable to the autografts, but the former showed a high incidence of aneurysm formation as a result of immune rejection as supported by histopathological and scanning electron microscopy studies.

摘要

从新西兰白兔身上取出股动脉段并进行冷冻干燥。然后将其用作斯普拉格-道利大鼠股动脉缺损的移植物。该受体大鼠另一侧的股动脉采用其自身股动脉段进行类似的移植手术,以此作为对照。冷冻干燥异种移植物的通畅率与自体移植物相当,但前者因免疫排斥导致动脉瘤形成的发生率较高,组织病理学和扫描电子显微镜研究证实了这一点。

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