Department of General Internal Medicine 2, General Medical Center, Kawasaki Medical School, Japan.
Department of Health Care Medicine, General Medical Center, Kawasaki Medical School, Japan.
Intern Med. 2023 Feb 1;62(3):381-386. doi: 10.2169/internalmedicine.8741-21. Epub 2022 Jun 7.
Two adult cases of acute gastric mucosal lesions (AGML) caused by Helicobacter pylori infection were confirmed by spontaneous eradication during the follow-up period. The clinical course of the initial infection by H. pylori in adults with AGML remains unclear, whether it is transient or progresses to a persistent infection. In these two reported cases, gastric biopsies at the time of the onset revealed the presence of H. pylori; however, serum H. pylori antibodies performed at the same time were negative. Retesting for H. pylori serum antibody, after six months in one and after two months in the other, was negative, confirming spontaneous eradication.
两例成人急性胃黏膜病变（AGML）由幽门螺杆菌感染引起，在随访期间被自发清除所证实。成人初次感染幽门螺杆菌后，其临床病程仍不清楚，是一过性的还是进展为持续性感染。在这两例报告病例中，发病时的胃活检显示存在幽门螺杆菌；然而，同时进行的血清幽门螺杆菌抗体检测呈阴性。在一例患者中，经过 6 个月后再次检测血清抗体，另一例患者经过 2 个月后再次检测，结果均为阴性，证实了自发清除。
