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通过DNA指纹图谱获得的直接证据表明,幽门螺杆菌的内镜交叉感染是内镜检查后急性胃炎的一个病因。

Direct evidence by DNA fingerprinting that endoscopic cross-infection of Helicobacter pylori is a cause of postendoscopic acute gastritis.

作者信息

Sugiyama T, Naka H, Yachi A, Asaka M

机构信息

Third Department of Internal Medicine, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

J Clin Microbiol. 2000 Jun;38(6):2381-2. doi: 10.1128/JCM.38.6.2381-2382.2000.

Abstract

The DNA fingerprinting of Helicobacter pylori strains in two cases of acute gastritis that occurred after endoscopy was examined. H. pylori was isolated from the stomachs of two patients with acute gastritis and from the stomachs of the patients in whom the same gastrofiberscope had previously been used. The genomic DNA digested with HaeIII was subjected to pulsed-field gel electrophoresis. The corresponding paired electrophoretic patterns were completely identical. These findings provide direct evidence that postendoscopic acute gastritis can be caused by cross-infection with H. pylori via endoscopy.

摘要

对两例内镜检查后发生的急性胃炎患者的幽门螺杆菌菌株进行了DNA指纹分析。从两名急性胃炎患者的胃中以及先前使用过同一台胃镜的患者胃中分离出幽门螺杆菌。用HaeIII消化的基因组DNA进行脉冲场凝胶电泳。相应的配对电泳图谱完全相同。这些发现提供了直接证据,证明内镜检查后急性胃炎可由幽门螺杆菌通过内镜交叉感染引起。

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